Measurements of [11C]CO2 in exhaled air with a positron-sensitive single-wire proportional counter after i.v. injection of [11C]acetate

Hannu T. Sipila*, Sven Johan Heselius, Matti K. Kalliokoski, Jukka Kemppainen, Heikki Minn, Tuula Tolvanen, Anne Roivainen

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionScientificpeer-review

Abstract

A positron-sensitive, large-window single-wire proportional counter was used for measurements of [11C]CO2 in exhaled air after i.v. injection of [11C]acetate. The performance of the proportional counter was studied using Geant4 and Garfield simulation tools as well as experimentally by injections of known amounts of radioactive gas into the measuring volume. The proportional counter was found to be sensitive enough for measuring the low concentrations of [11C]CO2 in the air exhaled by patients after i.v. injection of an 11C-labelled radiopharmaceutical. The limit of detection was 200 Bq/L for [ 11C]CO2.

Original languageEnglish
Title of host publication2011 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2011
PublisherIEEE
Pages2397-2399
Number of pages3
ISBN (Print)9781467301183
DOIs
Publication statusPublished - 1 Jan 2011
MoE publication typeA4 Article in a conference publication
EventIEEE Nuclear Science Symposium and Medical Imaging Conference - Valencia, Spain
Duration: 23 Oct 201129 Oct 2011

Publication series

NameIEEE Nuclear Science Symposium Conference Record
ISSN (Print)1095-7863

Conference

ConferenceIEEE Nuclear Science Symposium and Medical Imaging Conference
Abbreviated titleNSS/MIC
CountrySpain
CityValencia
Period23/10/201129/10/2011

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