Lipase-Induced Oxidative Furan Rearrangements

Fabian Blume, Petra Sprengart, Jan Deska

Research output: Contribution to journalArticleScientificpeer-review

5 Citations (Scopus)
104 Downloads (Pure)

Abstract

Lipase B from Candida antarctica catalyzes the oxidative ring expansion of furfuryl alcohols using aqueous hydrogen peroxide to yield functionalized pyranones under mild conditions. The method further allows for the preparation of corresponding piperidinone derivatives by enzymatic rearrangement of N-protected furfurylamines.

Original languageEnglish
Pages (from-to)1293-1296
Number of pages4
JournalSynlett
Volume29
Issue number10
DOIs
Publication statusPublished - 15 Jan 2018
MoE publication typeA1 Journal article-refereed

Keywords

  • Achmatowicz
  • furan
  • heterocyclic chemistry
  • pyranone
  • ring expansion
  • synthetic methodology

Fingerprint Dive into the research topics of 'Lipase-Induced Oxidative Furan Rearrangements'. Together they form a unique fingerprint.

  • Projects

    Beyond Biosynthesis: Enzymes as Catalysts in Non-natural Synthetic Transformations

    Blume, F., Jäger, C., Deska, J., Naapuri, J., Liu, Y. & Kiefer, A.

    01/09/201631/08/2021

    Project: Academy of Finland: Other research funding

    Equipment

  • Cite this