Lignin for Nano- and Microscaled Carrier Systems: Applications, Trends, and Challenges

Mika Henrikki Sipponen*, Heiko Lange, Claudia Crestini, Alexander Henn, Monika Österberg

*Corresponding author for this work

Research output: Contribution to journalReview Articlepeer-review

4 Citations (Scopus)
300 Downloads (Pure)


To liberate society from its dependence on fossil-based fuels and materials it is pivotal to explore components of renewable plant biomass in applications that benefit from their intrinsic biodegradability, safety, and sustainability. Lignin, a byproduct of the pulp and paper industry, is a plausible material for carrying various types of cargo in small- and large-scale applications. Herein, possibilities and constraints regarding the physical–chemical properties of the lignin source as well as modifications and processing required to render lignins suitable for the loading and release of pesticides, pharmaceuticals, and biological macromolecules is reviewed. In addition, the technical challenges, regulatory and toxicological aspects, and future research needed to realize some of the promises that nano- and microscaled lignin materials hold for a sustainable future are critically discussed.

Original languageEnglish
Pages (from-to)2039-2054
Number of pages16
Issue number10
Publication statusPublished - 21 May 2019
MoE publication typeA2 Review article in a scientific journal


  • drug delivery
  • immobilization
  • lignin
  • nanoparticles
  • sustainable chemistry


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