Light-Responsive Dynamic DNA-Origami-Based Plasmonic Assemblies

Joonas Ryssy, Ashwin K. Natarajan, Jinhua Wang, Arttu J Lehtonen, Kha Nguyen, Rafal Klajn, Anton Kuzyk

Research output: Contribution to journalArticleScientificpeer-review

Abstract

DNA nanotechnology offers a versatile toolbox for precise spatial and temporal manipulation of matter on the nanoscale. However, rendering DNA-based systems responsive to light has remained challenging. Here, we describe the remote manipulation of native (non-photoresponsive) chiral plasmonic molecules (CPMs) using light. Our strategy is based on the use of a photoresponsive medium comprising a merocyanine-based photoacid. Upon exposure to visible light, the medium decreases its pH, inducing the formation of DNA triplex links, leading to a spatial reconfiguration of the CPMs. The process can be reversed simply by turning the light off and it can be repeated for multiple cycles. The degree of the overall chirality change in an ensemble of CPMs depends on the CPM fraction undergoing reconfiguration, which, remarkably, depends on and can be tuned by the intensity of incident light. Such a dynamic remotely controlled system could aid in further advancing DNA-based devices and nanomaterials.
Original languageEnglish
Number of pages4
JournalAngewandte Chemie
DOIs
Publication statusE-pub ahead of print - 15 Dec 2020
MoE publication typeA1 Journal article-refereed

Keywords

  • Chiral plasmonics
  • DNA origami
  • photoacid
  • self-assembly
  • Stimuli responsivematerials

Fingerprint Dive into the research topics of 'Light-Responsive Dynamic DNA-Origami-Based Plasmonic Assemblies'. Together they form a unique fingerprint.

Cite this