Ligand creation via linking - a rapid and convenient method for construction of novel supported PyOX-ligands

Ari M.P. Koskinen, Markku J. Oila, Jan E. Tois

    Research output: Contribution to journalArticleScientificpeer-review

    11 Citations (Scopus)
    124 Downloads (Pure)

    Abstract

    A novel supported amino alcohol linker was synthesized and utilized for attachment of picolinic acid derivatives onto different supports. When the resin bound molecule was further activated, the PyOX-moiety could be constructed reliably in enantiopure form. Furthermore, an efficient Pd-catalyzed modification of a picolinic acid derivative is presented.
    Original languageEnglish
    Pages (from-to)10748-10756
    JournalTetrahedron
    Issue number61
    Publication statusPublished - 2005
    MoE publication typeA1 Journal article-refereed

    Keywords

    • amino alcohol linker
    • picolinic acid derivative
    • supported PyOX-ligand
    • tyrosine

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