A novel supported amino alcohol linker was synthesized and utilized for attachment of picolinic acid derivatives onto different supports. When the resin bound molecule was further activated, the PyOX-moiety could be constructed reliably in enantiopure form. Furthermore, an efficient Pd-catalyzed modification of a picolinic acid derivative is presented.
|Publication status||Published - 2005|
|MoE publication type||A1 Journal article-refereed|
- amino alcohol linker
- picolinic acid derivative
- supported PyOX-ligand