KatF (σs) synthesis in Escherichia coli is subject to posttranscriptional regulation

Peter C. Loewen*, Ingemar von Ossowski, Jacek Switala, Michael R. Mulvey

*Corresponding author for this work

Research output: Contribution to journalComment/debateScientificpeer-review

Abstract

A transcriptional fusion of katF to the lacZ gene was expressed at increasingly higher levels throughout the exponential phase, but a translational fusion was expressed at low levels during exponential-phase growth and was induced 160-fold during the transition to stationary phase, implicating a posttranscriptional mechanism in the regulation of KatF synthesis. Mutational analyses suggested that the initiation codon of katF is the second ATG in the previously identified open reading frame.

Original languageEnglish
Pages (from-to)2150-2153
Number of pages4
JournalJournal of Bacteriology
Volume175
Issue number7
DOIs
Publication statusPublished - Apr 1993
MoE publication typeA1 Journal article-refereed

Keywords

  • MESSENGER-RNA
  • TRANSCRIPTION
  • EXPRESSION
  • INITIATION
  • PROTEIN
  • SINGLE

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