Projects per year
Precise genome editing with CRISPR/Cas paves the way for many biochemical, biotechnological, and medical applications, and consequently, it may enable treatment of already known and still-to-be-found genetic diseases. Meanwhile, another rapidly emerging field—structural DNA nanotechnology—provides a customizable and modular platform for accurate positioning of nanoscopic materials, for e.g., biomedical uses. This addressability has just recently been applied in conjunction with the newly developed gene engineering tools to enable impactful, programmable nanotechnological applications. As of yet, self-assembled DNA nanostructures have been mainly employed to enhance and direct the delivery of CRISPR/Cas, but lately the groundwork has also been laid out for other intriguing and complex functions. These recent advances will be described in this perspective.
|Number of pages||12|
|Early online date||22 May 2022|
|Publication status||Published - 17 Jun 2022|
|MoE publication type||A2 Review article in a scientific journal|
FingerprintDive into the research topics of 'Integrating CRISPR/Cas systems with programmable DNA nanostructures for delivery and beyond'. Together they form a unique fingerprint.
- 1 Active
Center of Excellence in Life-Inspired Hybrid Materials
Kostiainen, M. & Luotonen, O.
01/01/2022 → 31/12/2024
Project: Academy of Finland: Other research funding