Indoor chaetomium-like isolates: resistance to chemicals, fluorescence and mycotoxin production

Emmanuelle Castagnoli; M.A.  Andersson; Raimo Mikkola; Laszlo Kredics; Tamás Marik; Jarek Kurnitski; Heidi Salonen

Indoor chaetomium-like isolates: resistance to chemicals, fluorescence and mycotoxin production

Emmanuelle Castagnoli, M.A. Andersson, Raimo Mikkola, Laszlo Kredics, Tamás Marik, Jarek Kurnitski, Heidi Salonen

Department of Civil Engineering

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Professional

Abstract

Chaetomium-like fungi growing on indoor building materials produce toxic substances. Fourteen toxigenic indoor Chaetomium-like isolates from buildings in Finland where investigated. Six Chaetomium globosum-like strains from indoor dusts were toxic with boar sperm assay and cytotoxic to porcine kidney cells (PK-15), emitted green fluorescence and produced chaetoglobosins inhibiting cellular glucose transport. OT7 and OT7b strains fromindoor dust were cytotoxic to PK-15 cells, non fluorescent and produced the extremely cytotoxic protein synthesis inhibitor, chaetomin. The six Chaetomium globosum-like strains were resistant to borax and very sensitive to the wetting agent genapol used in cleaning chemicals. This may indicate that indoor Chaetomium-like fungi occupy their own ecological niche in buildings.

Original language	English
Title of host publication	Sisäilmastoseminaari 2017, Helsinki, 15.03.2017
Editors	Jorma Säteri, Mervi Ahola
Publisher	Sisäilmayhdistys ry
Pages	227-232
Volume	35
ISBN (Print)	978-952-5236-45-3
Publication status	Published - 15 Mar 2017
MoE publication type	D3 Professional conference proceedings
Event	Sisäilmastoseminaari - Messukeskus, Helsinki, Finland Duration: 15 Mar 2017 → 15 Mar 2017 http://www.sisailmayhdistys.fi/Tapahtumat/Sisailmastoseminaarit/Sisailmastoseminaari-2017

Publication series

Name	SIY raportti 35
Publisher	Sisäilmayhdistys ry
ISSN (Print)	1237-1866

Conference

Conference	Sisäilmastoseminaari
Country/Territory	Finland
City	Helsinki
Period	15/03/2017 → 15/03/2017
Internet address	http://www.sisailmayhdistys.fi/Tapahtumat/Sisailmastoseminaarit/Sisailmastoseminaari-2017

Keywords

Chaetomium-like

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Castagnoli, Emmanuelle ; Andersson, M.A. ; Mikkola, Raimo ; Kredics, Laszlo ; Marik, Tamás ; Kurnitski, Jarek ; Salonen, Heidi. / Indoor chaetomium-like isolates: resistance to chemicals, fluorescence and mycotoxin production. Sisäilmastoseminaari 2017, Helsinki, 15.03.2017. editor / Jorma Säteri ; Mervi Ahola. Vol. 35 Sisäilmayhdistys ry, 2017. pp. 227-232 (SIY raportti 35).

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abstract = "Chaetomium-like fungi growing on indoor building materials produce toxic substances. Fourteen toxigenic indoor Chaetomium-like isolates from buildings in Finland where investigated. Six Chaetomium globosum-like strains from indoor dusts were toxic with boar sperm assay and cytotoxic to porcine kidney cells (PK-15), emitted green fluorescence and produced chaetoglobosins inhibiting cellular glucose transport. OT7 and OT7b strains fromindoor dust were cytotoxic to PK-15 cells, non fluorescent and produced the extremely cytotoxic protein synthesis inhibitor, chaetomin. The six Chaetomium globosum-like strains were resistant to borax and very sensitive to the wetting agent genapol used in cleaning chemicals. This may indicate that indoor Chaetomium-like fungi occupy their own ecological niche in buildings.",

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Castagnoli, E , Andersson, MA , Mikkola, R, Kredics, L, Marik, T, Kurnitski, J & Salonen, H 2017, Indoor chaetomium-like isolates: resistance to chemicals, fluorescence and mycotoxin production. in J Säteri & M Ahola (eds), Sisäilmastoseminaari 2017, Helsinki, 15.03.2017. vol. 35, SIY raportti 35, Sisäilmayhdistys ry, pp. 227-232, Sisäilmastoseminaari, Helsinki, Finland, 15/03/2017.

Indoor chaetomium-like isolates: resistance to chemicals, fluorescence and mycotoxin production. / Castagnoli, Emmanuelle ; Andersson, M.A. ; Mikkola, Raimo; Kredics, Laszlo; Marik, Tamás; Kurnitski, Jarek ; Salonen, Heidi.

Sisäilmastoseminaari 2017, Helsinki, 15.03.2017. ed. / Jorma Säteri; Mervi Ahola. Vol. 35 Sisäilmayhdistys ry, 2017. p. 227-232 (SIY raportti 35).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Professional

TY - GEN

T1 - Indoor chaetomium-like isolates: resistance to chemicals, fluorescence and mycotoxin production

AU - Castagnoli, Emmanuelle

AU - Andersson, M.A.

AU - Mikkola, Raimo

AU - Kredics, Laszlo

AU - Marik, Tamás

AU - Kurnitski, Jarek

AU - Salonen, Heidi

PY - 2017/3/15

Y1 - 2017/3/15

N2 - Chaetomium-like fungi growing on indoor building materials produce toxic substances. Fourteen toxigenic indoor Chaetomium-like isolates from buildings in Finland where investigated. Six Chaetomium globosum-like strains from indoor dusts were toxic with boar sperm assay and cytotoxic to porcine kidney cells (PK-15), emitted green fluorescence and produced chaetoglobosins inhibiting cellular glucose transport. OT7 and OT7b strains fromindoor dust were cytotoxic to PK-15 cells, non fluorescent and produced the extremely cytotoxic protein synthesis inhibitor, chaetomin. The six Chaetomium globosum-like strains were resistant to borax and very sensitive to the wetting agent genapol used in cleaning chemicals. This may indicate that indoor Chaetomium-like fungi occupy their own ecological niche in buildings.

AB - Chaetomium-like fungi growing on indoor building materials produce toxic substances. Fourteen toxigenic indoor Chaetomium-like isolates from buildings in Finland where investigated. Six Chaetomium globosum-like strains from indoor dusts were toxic with boar sperm assay and cytotoxic to porcine kidney cells (PK-15), emitted green fluorescence and produced chaetoglobosins inhibiting cellular glucose transport. OT7 and OT7b strains fromindoor dust were cytotoxic to PK-15 cells, non fluorescent and produced the extremely cytotoxic protein synthesis inhibitor, chaetomin. The six Chaetomium globosum-like strains were resistant to borax and very sensitive to the wetting agent genapol used in cleaning chemicals. This may indicate that indoor Chaetomium-like fungi occupy their own ecological niche in buildings.

KW - Chaetomium-like

UR - http://www.sisailmayhdistys.fi/Tapahtumat/Sisailmastoseminaarit/Sisailmastoseminaari-2017

M3 - Conference contribution

SN - 978-952-5236-45-3

VL - 35

T3 - SIY raportti 35

SP - 227

EP - 232

BT - Sisäilmastoseminaari 2017, Helsinki, 15.03.2017

A2 - Säteri, Jorma

A2 - Ahola, Mervi

PB - Sisäilmayhdistys ry

T2 - Sisäilmastoseminaari

Y2 - 15 March 2017 through 15 March 2017

ER -

Indoor chaetomium-like isolates: resistance to chemicals, fluorescence and mycotoxin production

Abstract

Publication series

Conference

Keywords

SFX availability

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Toxin transport mechanisms from moisture damaged structures to indoor air

Cite this

Indoor chaetomium-like isolates: resistance to chemicals, fluorescence and mycotoxin production

Abstract

Publication series

Conference

Keywords

SFX availability

Other files and links

Fingerprint

Projects

Toxin transport mechanisms from moisture damaged structures to indoor air

Cite this