Indoor chaetomium-like isolates: resistance to chemicals, fluorescence and mycotoxin production

Research output: Chapter in Book/Report/Conference proceedingConference article in proceedingsProfessional


Chaetomium-like fungi growing on indoor building materials produce toxic substances. Fourteen toxigenic indoor Chaetomium-like isolates from buildings in Finland where investigated. Six Chaetomium globosum-like strains from indoor dusts were toxic with boar sperm assay and cytotoxic to porcine kidney cells (PK-15), emitted green fluorescence and produced chaetoglobosins inhibiting cellular glucose transport. OT7 and OT7b strains fromindoor dust were cytotoxic to PK-15 cells, non fluorescent and produced the extremely cytotoxic protein synthesis inhibitor, chaetomin. The six Chaetomium globosum-like strains were resistant to borax and very sensitive to the wetting agent genapol used in cleaning chemicals. This may indicate that indoor Chaetomium-like fungi occupy their own ecological niche in buildings.
Original languageEnglish
Title of host publicationSisäilmastoseminaari 2017, Helsinki, 15.03.2017
EditorsJorma Säteri, Mervi Ahola
PublisherSisäilmayhdistys Ry
ISBN (Print)978-952-5236-45-3
Publication statusPublished - 15 Mar 2017
MoE publication typeD3 Professional conference proceedings
EventSisäilmastoseminaari - Messukeskus, Helsinki, Finland
Duration: 15 Mar 201715 Mar 2017

Publication series

NameSIY raportti 35
PublisherSisäilmayhdistys ry
ISSN (Print)1237-1866


Internet address


  • Chaetomium-like


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