Immunoassay of β2-microglobulin at oxide-coated heavily doped p-silicon electrodes

Markus Håkansson, Kalle Salminen, Päivi Kuosmanen, Jarkko Eskola, Heikki Peuravuori, Sakari Kulmala*

*Corresponding author for this work

    Research output: Contribution to journalArticleScientificpeer-review

    8 Citations (Scopus)


    An immunoassay was carried out on disposable oxide-coated silicon chip electrodes made of heavily doped p-type silicon, simply thermally oxidized in room air in a laboratory oven. The present electrode chips allow injection of hot electrons into aqueous electrolyte solutions and can be utilized in detecting electrochemiluminescent labels in fully aqueous solutions. This is demonstrated with an immunoassay of β2-microglobulin using an aromatic Tb(III) chelate as an electrochemiluminescent label.

    Original languageEnglish
    Pages (from-to)11-15
    Number of pages5
    JournalJournal of Electroanalytical Chemistry
    Publication statusPublished - 15 May 2016
    MoE publication typeA1 Journal article-refereed


    • Bioaffinity assay
    • Electrogenerated chemiluminescence
    • Hot electron-induced electrochemiluminescence
    • Immunoassays
    • Tb(III) chelates


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