Immunoassay based on hot electron induced electrochemiluminescense on disposable cell chips with printed electrodes

null Nur-E-Habiba; Kalle Salminen; Päivi Grönroos; Esko Kauppinen; Veikko Sariola; Sakari Kulmala

Immunoassay based on hot electron induced electrochemiluminescense on disposable cell chips with printed electrodes

Nur-E-Habiba^*, Kalle Salminen, Päivi Grönroos, Esko Kauppinen, Veikko Sariola, Sakari Kulmala

^*Corresponding author for this work

Tampere University

Research output: Contribution to conference › Abstract › Scientific › peer-review

Abstract

This paper reports utilization of Hot Electron-induced Electrochemiluminescence (HECL) on inexpensive disposable printed electrode chips for the first time. HECL method typically utilizes luminophores as labels in sensitive bioaffinity-based assays. Here we demonstrate HECL, as a novel approach by using a widely used fluorescent probe - fluorescein isothiocyanate (FITC) as luminophore label for human C-reactive protein (hCRP)assay. Our work results in a combined benefit of the integration of HECL on disposable electrode chip and the utilization of the low-cost FITC, resulting in successful real-world heterogeneous immunoassay development, and thus paving the way for being used in point of care devices.

Original language	English
Pages	1268-1269
Number of pages	2
Publication status	Published - 2019
MoE publication type	Not Eligible
Event	International Conference on Miniaturized Systems for Chemistry and Life Sciences - Basel, Switzerland Duration: 27 Oct 2019 → 31 Oct 2019 Conference number: 23

Conference

Conference	International Conference on Miniaturized Systems for Chemistry and Life Sciences
Abbreviated title	MicroTAS
Country/Territory	Switzerland
City	Basel
Period	27/10/2019 → 31/10/2019

Keywords

Hot Electron-induced Electrochemiluminescence
Human C-reactive Protein
Immunoassay

Cite this

@conference{694d6c1678914736ad135835850b36da,

title = "Immunoassay based on hot electron induced electrochemiluminescense on disposable cell chips with printed electrodes",

abstract = "This paper reports utilization of Hot Electron-induced Electrochemiluminescence (HECL) on inexpensive disposable printed electrode chips for the first time. HECL method typically utilizes luminophores as labels in sensitive bioaffinity-based assays. Here we demonstrate HECL, as a novel approach by using a widely used fluorescent probe - fluorescein isothiocyanate (FITC) as luminophore label for human C-reactive protein (hCRP)assay. Our work results in a combined benefit of the integration of HECL on disposable electrode chip and the utilization of the low-cost FITC, resulting in successful real-world heterogeneous immunoassay development, and thus paving the way for being used in point of care devices.",

keywords = "Hot Electron-induced Electrochemiluminescence, Human C-reactive Protein, Immunoassay",

author = "Nur-E-Habiba and Kalle Salminen and P{\"a}ivi Gr{\"o}nroos and Esko Kauppinen and Veikko Sariola and Sakari Kulmala",

year = "2019",

language = "English",

pages = "1268--1269",

note = "International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS ; Conference date: 27-10-2019 Through 31-10-2019",

}

Immunoassay based on hot electron induced electrochemiluminescense on disposable cell chips with printed electrodes. / Nur-E-Habiba; Salminen, Kalle; Grönroos, Päivi et al.
2019. 1268-1269 Abstract from International Conference on Miniaturized Systems for Chemistry and Life Sciences, Basel, Switzerland.

Research output: Contribution to conference › Abstract › Scientific › peer-review

TY - CONF

T1 - Immunoassay based on hot electron induced electrochemiluminescense on disposable cell chips with printed electrodes

AU - Nur-E-Habiba, null

AU - Salminen, Kalle

AU - Grönroos, Päivi

AU - Kauppinen, Esko

AU - Sariola, Veikko

AU - Kulmala, Sakari

N1 - Conference code: 23

PY - 2019

Y1 - 2019

N2 - This paper reports utilization of Hot Electron-induced Electrochemiluminescence (HECL) on inexpensive disposable printed electrode chips for the first time. HECL method typically utilizes luminophores as labels in sensitive bioaffinity-based assays. Here we demonstrate HECL, as a novel approach by using a widely used fluorescent probe - fluorescein isothiocyanate (FITC) as luminophore label for human C-reactive protein (hCRP)assay. Our work results in a combined benefit of the integration of HECL on disposable electrode chip and the utilization of the low-cost FITC, resulting in successful real-world heterogeneous immunoassay development, and thus paving the way for being used in point of care devices.

AB - This paper reports utilization of Hot Electron-induced Electrochemiluminescence (HECL) on inexpensive disposable printed electrode chips for the first time. HECL method typically utilizes luminophores as labels in sensitive bioaffinity-based assays. Here we demonstrate HECL, as a novel approach by using a widely used fluorescent probe - fluorescein isothiocyanate (FITC) as luminophore label for human C-reactive protein (hCRP)assay. Our work results in a combined benefit of the integration of HECL on disposable electrode chip and the utilization of the low-cost FITC, resulting in successful real-world heterogeneous immunoassay development, and thus paving the way for being used in point of care devices.

KW - Hot Electron-induced Electrochemiluminescence

KW - Human C-reactive Protein

KW - Immunoassay

UR - http://www.scopus.com/inward/record.url?scp=85094976169&partnerID=8YFLogxK

M3 - Abstract

AN - SCOPUS:85094976169

SP - 1268

EP - 1269

T2 - International Conference on Miniaturized Systems for Chemistry and Life Sciences

Y2 - 27 October 2019 through 31 October 2019

ER -

Immunoassay based on hot electron induced electrochemiluminescense on disposable cell chips with printed electrodes

Abstract

Conference

Keywords

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