Immobilized cytochrome P450 microreactors with integrated heaters

Iiro Kiiski*, Sari Tähkä, Gowtham Sathyanarayanan, Markus Haapala, Ville Jokinen, Tiina Sikanen

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionScientificpeer-review

1 Citation (Scopus)

Abstract

In this work, new biofunctionalization approaches targeting immobilization of cytochrome P450 (CYP) enzymes on thiol-ene based micropillar arrays were developed including integration of thin-film heaters and characterization of the throughput of immobilized CYP enzyme microreactors (CYP-IMERs).

Original languageEnglish
Title of host publication20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016
Pages645-646
Number of pages2
ISBN (Electronic)9780979806490
Publication statusPublished - 2016
MoE publication typeA4 Article in a conference publication
EventInternational Conference on Miniaturized Systems for Chemistry and Life Sciences - Dublin, Ireland
Duration: 9 Oct 201613 Oct 2016
Conference number: 20

Conference

ConferenceInternational Conference on Miniaturized Systems for Chemistry and Life Sciences
Abbreviated titleMicroTAS 2016
CountryIreland
CityDublin
Period09/10/201613/10/2016

Keywords

  • Cytochrome P450
  • Drug metabolism
  • Immobilized enzyme microreactors
  • Thiol-enes

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