Idiosyncratic responding during movie-watching predicted by age differences in attentional control

Karen L. Campbell*, Meredith A. Shafto, Paul Wright, Kamen A. Tsvetanov, Linda Geerligs, Rhodri Cusack, Cam-Can, Lorraine K. Tyler, Nitin Williams

*Corresponding author for this work

Research output: Contribution to journalArticleScientificpeer-review

Abstract

Much is known about how age affects the brain during tightly controlled, though largely contrived, experiments, but do these effects extrapolate to everyday life? Naturalistic stimuli, such as movies, closely mimic the real world and provide a window onto the brain's ability to respond in a timely and measured fashion to complex, everyday events. Young adults respond to these stimuli in a highly synchronized fashion, but it remains to be seen how age affects neural responsiveness during naturalistic viewing. To this end, we scanned a large (N = 218), population-based sample from the Cambridge Centre for Ageing and Neuroscience (Cam-CAN) during movie-watching. Intersubject synchronization declined with age, such that older adults' response to the movie was more idiosyncratic. This decreased synchrony related to cognitive measures sensitive to attentional control. Our findings suggest that neural responsivity changes with age, which likely has important implications for real-world event comprehension and memory. (C) 2015 The Authors. Published by Elsevier Inc.

Original languageEnglish
Pages (from-to)3045-3055
Number of pages11
JournalNEUROBIOLOGY OF AGING
Volume36
Issue number11
DOIs
Publication statusPublished - Nov 2015
MoE publication typeA1 Journal article-refereed

Keywords

  • Natural vision
  • Aging
  • Attentional control
  • fMRI
  • Independent components analysis
  • Intersubject correlation
  • FUNCTIONAL CONNECTIVITY MRI
  • RESTING-STATE FMRI
  • OLDER-ADULTS
  • PREFRONTAL CORTEX
  • COGNITIVE CONTROL
  • SUBJECT MOTION
  • BRAIN ACTIVITY
  • HEAD MOTION
  • LIFE-SPAN
  • MEMORY

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