Highly Stereoselective Allylic Alkylations of Peptides

Jan Deska, Uli Kazmaier, Anja Watzke

Research output: Contribution to journalArticleScientificpeer-review


Palladium-catalyzed allylic alkylations are extremely suitable for the stereoselective introduction of unsaturated side chains to peptides (see scheme; TFA=trifluoroacetate). The chiral information of the peptide can be used to control the formation of the new stereogenic center. In general, S amino acids induce the formation of R-configured amino acids.
Original languageEnglish
Pages (from-to)4855-4858
Number of pages4
JournalAngewandte Chemie - International Edition
Issue number29
Publication statusPublished - 10 Jul 2006
MoE publication typeA1 Journal article-refereed


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