Highly diastereoselective methylation of (2S,4S)- and (2R,4S)-3-tert-butyl 4-methyl 2-tertbutyloxazolidine-3,4-dicarboxylate (1a/b) is reported. The relative and absolute configuration of the methylated products was assigned by NOESY and confirmed by a crystal structure of 1a.
|Number of pages||3|
|Journal||Letters in Organic Chemistry|
|Publication status||Published - 2004|
|MoE publication type||A1 Journal article-refereed|
- amino acids