Highly Chemoselective Copper-Catalyzed Conjugate Reduction of Stereochemically Labile alpha,beta-Unsaturated Amino Ketones

Research output: Scientific - peer-reviewArticle

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Original languageEnglish
Pages (from-to)7598-7601
JournalJOURNAL OF ORGANIC CHEMISTRY
Volume74
Issue number19
StatePublished - 2009
MoE publication typeA1 Journal article-refereed

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Abstract

Highly chemoselective conjugate reduction of chiral R,β-unsaturated amino ketones has been developed by using triisopropyl phosphite ligated copper hydride complex. The highlights of the method are wide substrate compatibility and exceptional chemoselectivity.

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ID: 2379561