FUNGAL PROMOTERS ACTIVE IN THE PRESENCE OF GLUCOSE

Tiina Nakari; Maija-Leena Onnela; Marja H.  Ilmen; Merja Penttilä; Kaisu M. H.  Nevalainen

FUNGAL PROMOTERS ACTIVE IN THE PRESENCE OF GLUCOSE

Tiina Nakari (Inventor), Maija-Leena Onnela (Inventor), Marja H. Ilmen (Inventor), Merja Penttilä (Inventor), Kaisu M. H. Nevalainen (Inventor)

Not published at Aalto University

VTT Technical Research Centre of Finland

Research output: Patent

Abstract

2142602 9404673 PCTABS00030 A method is described for the identification and cloning of promoters that express under a defined environmental condition, such as growth in glucose medium. Using this method, five Trichodermal promoters capable of the high expression of operably linked coding sequences are identified, one of which is the promoter for T. reesei tef1. Also provided are altered cbh1 promoters, altered so that glucose no longer represses expression from such promoter. The invention further provides vectors and hosts that utilize such promoters, and unique fungal enzyme compositions from such hosts.

Original language	English
Patent number	CA2142602
IPC	C12R 1/ 885 A N
Priority date	19/08/1992
Publication status	Published - 3 Mar 1994
MoE publication type	H1 Granted patent

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abstract = "2142602 9404673 PCTABS00030 A method is described for the identification and cloning of promoters that express under a defined environmental condition, such as growth in glucose medium. Using this method, five Trichodermal promoters capable of the high expression of operably linked coding sequences are identified, one of which is the promoter for T. reesei tef1. Also provided are altered cbh1 promoters, altered so that glucose no longer represses expression from such promoter. The invention further provides vectors and hosts that utilize such promoters, and unique fungal enzyme compositions from such hosts.",

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T1 - FUNGAL PROMOTERS ACTIVE IN THE PRESENCE OF GLUCOSE

AU - Nakari, Tiina

AU - Onnela, Maija-Leena

AU - Ilmen, Marja H.

AU - Penttilä, Merja

AU - Nevalainen, Kaisu M. H.

PY - 1994/3/3

Y1 - 1994/3/3

N2 - 2142602 9404673 PCTABS00030 A method is described for the identification and cloning of promoters that express under a defined environmental condition, such as growth in glucose medium. Using this method, five Trichodermal promoters capable of the high expression of operably linked coding sequences are identified, one of which is the promoter for T. reesei tef1. Also provided are altered cbh1 promoters, altered so that glucose no longer represses expression from such promoter. The invention further provides vectors and hosts that utilize such promoters, and unique fungal enzyme compositions from such hosts.

AB - 2142602 9404673 PCTABS00030 A method is described for the identification and cloning of promoters that express under a defined environmental condition, such as growth in glucose medium. Using this method, five Trichodermal promoters capable of the high expression of operably linked coding sequences are identified, one of which is the promoter for T. reesei tef1. Also provided are altered cbh1 promoters, altered so that glucose no longer represses expression from such promoter. The invention further provides vectors and hosts that utilize such promoters, and unique fungal enzyme compositions from such hosts.

M3 - Patent

M1 - CA2142602

ER -

FUNGAL PROMOTERS ACTIVE IN THE PRESENCE OF GLUCOSE

Abstract

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