Abstract
Virus particles are naturally occurring nanomaterials. They are widely recognized as excellent templates for fabrication of functional nanomaterials due to their nat¬urally occurring nanoscale size, ease of production, monodispersity in terms of composition/size/shape, stability, programmability, and biodegradability. Plant virus particles are completely noninfectious to humankind. In addition, the pros¬pect of cost-effective production in plants, ease of tailoring via genetic engineering or chemical modifications and excellent biocompatibility are some of the features that makes plant viruses a game changer in biomedical sectors. Unlike icosahe- dral viruses like cowpea mosaic virus (CPMV) and cowpea chlorotic mosaic virus (CCMV) or rigid rod-shaped viruses like Tobacco mosaic virus (TMV), flexuous plant viruses are drastically less studied. This chapter encompasses general intro¬duction on plant viruses, followed by discussions focused on flexuous plant virus particles, their structures and production platforms. Finally, their functionaliza¬tion and uses in biomedical sectors are summarized.
| Original language | English |
|---|---|
| Title of host publication | Nanomaterials in Clinical Therapeutics |
| Subtitle of host publication | Synthesis and Applications |
| Editors | Mainak Mukhopadhay, Arindam Kuila |
| Publisher | Wiley |
| Pages | 205-223 |
| Number of pages | 19 |
| ISBN (Electronic) | 978-1-119-85774-7 |
| ISBN (Print) | 978-1-119-85723-5 |
| DOIs | |
| Publication status | Published - 16 Aug 2022 |
| MoE publication type | A3 Book section, Chapters in research books |
Keywords
- Drug delivery
- Immunotherapy
- Potexvirus
- Potyvirus
- Virus nanotechnology
- Virus-like particles