Flexible Micropillar Electrode Arrays for In Vivo Neural Activity Recordings

Research output: Contribution to journalArticle

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Flexible Micropillar Electrode Arrays for In Vivo Neural Activity Recordings. / Du, Mingde; Guan, Shouliang; Gao, Lei; Lv, Suye; Yang, Siting; Shi, Jidong; Wang, Jinfen; Li, Hongbian; Fang, Ying.

In: Small, Vol. 15, No. 20, 1900582, 17.05.2019.

Research output: Contribution to journalArticle

Harvard

Du, M, Guan, S, Gao, L, Lv, S, Yang, S, Shi, J, Wang, J, Li, H & Fang, Y 2019, 'Flexible Micropillar Electrode Arrays for In Vivo Neural Activity Recordings', Small, vol. 15, no. 20, 1900582. https://doi.org/10.1002/smll.201900582

APA

Du, M., Guan, S., Gao, L., Lv, S., Yang, S., Shi, J., ... Fang, Y. (2019). Flexible Micropillar Electrode Arrays for In Vivo Neural Activity Recordings. Small, 15(20), [1900582]. https://doi.org/10.1002/smll.201900582

Vancouver

Author

Du, Mingde ; Guan, Shouliang ; Gao, Lei ; Lv, Suye ; Yang, Siting ; Shi, Jidong ; Wang, Jinfen ; Li, Hongbian ; Fang, Ying. / Flexible Micropillar Electrode Arrays for In Vivo Neural Activity Recordings. In: Small. 2019 ; Vol. 15, No. 20.

Bibtex - Download

@article{726eb44b428e48aca189fc41aeb282aa,
title = "Flexible Micropillar Electrode Arrays for In Vivo Neural Activity Recordings",
abstract = "Flexible electronics that can form tight interfaces with neural tissues hold great promise for improving the diagnosis and treatment of neurological disorders and advancing brain/machine interfaces. Here, the facile fabrication of a novel flexible micropillar electrode array (µPEA) is described based on a biotemplate method. The flexible and compliant µPEA can readily integrate with the soft surface of a rat cerebral cortex. Moreover, the recording sites of the µPEA consist of protruding micropillars with nanoscale surface roughness that ensure tight interfacing and efficient electrical coupling with the nervous system. As a result, the flexible µPEA allows for in vivo multichannel recordings of epileptiform activity with a high signal-to-noise ratio of 252 ± 35. The ease of preparation, high flexibility, and biocompatibility make the µPEA an attractive tool for in vivo spatiotemporal mapping of neural activity.",
keywords = "electrocorticography, epilepsy, flexible electronics, neural recording, subdural electrodes",
author = "Mingde Du and Shouliang Guan and Lei Gao and Suye Lv and Siting Yang and Jidong Shi and Jinfen Wang and Hongbian Li and Ying Fang",
note = "Tarkista embargo, kun artikkeli julkaistu.",
year = "2019",
month = "5",
day = "17",
doi = "10.1002/smll.201900582",
language = "English",
volume = "15",
journal = "Small",
issn = "1613-6810",
number = "20",

}

RIS - Download

TY - JOUR

T1 - Flexible Micropillar Electrode Arrays for In Vivo Neural Activity Recordings

AU - Du, Mingde

AU - Guan, Shouliang

AU - Gao, Lei

AU - Lv, Suye

AU - Yang, Siting

AU - Shi, Jidong

AU - Wang, Jinfen

AU - Li, Hongbian

AU - Fang, Ying

N1 - Tarkista embargo, kun artikkeli julkaistu.

PY - 2019/5/17

Y1 - 2019/5/17

N2 - Flexible electronics that can form tight interfaces with neural tissues hold great promise for improving the diagnosis and treatment of neurological disorders and advancing brain/machine interfaces. Here, the facile fabrication of a novel flexible micropillar electrode array (µPEA) is described based on a biotemplate method. The flexible and compliant µPEA can readily integrate with the soft surface of a rat cerebral cortex. Moreover, the recording sites of the µPEA consist of protruding micropillars with nanoscale surface roughness that ensure tight interfacing and efficient electrical coupling with the nervous system. As a result, the flexible µPEA allows for in vivo multichannel recordings of epileptiform activity with a high signal-to-noise ratio of 252 ± 35. The ease of preparation, high flexibility, and biocompatibility make the µPEA an attractive tool for in vivo spatiotemporal mapping of neural activity.

AB - Flexible electronics that can form tight interfaces with neural tissues hold great promise for improving the diagnosis and treatment of neurological disorders and advancing brain/machine interfaces. Here, the facile fabrication of a novel flexible micropillar electrode array (µPEA) is described based on a biotemplate method. The flexible and compliant µPEA can readily integrate with the soft surface of a rat cerebral cortex. Moreover, the recording sites of the µPEA consist of protruding micropillars with nanoscale surface roughness that ensure tight interfacing and efficient electrical coupling with the nervous system. As a result, the flexible µPEA allows for in vivo multichannel recordings of epileptiform activity with a high signal-to-noise ratio of 252 ± 35. The ease of preparation, high flexibility, and biocompatibility make the µPEA an attractive tool for in vivo spatiotemporal mapping of neural activity.

KW - electrocorticography

KW - epilepsy

KW - flexible electronics

KW - neural recording

KW - subdural electrodes

UR - http://www.scopus.com/inward/record.url?scp=85064496066&partnerID=8YFLogxK

U2 - 10.1002/smll.201900582

DO - 10.1002/smll.201900582

M3 - Article

VL - 15

JO - Small

JF - Small

SN - 1613-6810

IS - 20

M1 - 1900582

ER -

ID: 33510825