Fabrication of thiol-ene based electrophoresis chips with fully integrated electrospray ionization emitter by replication

Sari Tähkä; Ashkan Bonabi; Ville Jokinen; Tiina Sikanen

Fabrication of thiol-ene based electrophoresis chips with fully integrated electrospray ionization emitter by replication

Sari Tähkä^*
, Ashkan Bonabi
, Ville Jokinen
, Tiina Sikanen

^*Corresponding author for this work

Department of Chemistry and Materials Science

University of Helsinki

Research output: Chapter in Book/Report/Conference proceeding › Conference article in proceedings › Scientific › peer-review

Abstract

In this paper, for the first time, we report fabrication of free-standing (no carrier wafer) electrospray ionization (ESI) emitter tips as integral parts of thiol-ene-based electrophoresis chips. Integrated ESI tips enable their direct coupling to mass spectrometry (MS). In addition, we present performance characterization of the developed chips in ESI/MS analysis of peptides and small drug molecules.

Original language	English
Title of host publication	MicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences
Publisher	Chemical and Biological Microsystems Society (CBMS)
Pages	1758-1760
Number of pages	3
ISBN (Electronic)	978-0-9798064-8-3
Publication status	Published - 2015
MoE publication type	A4 Conference publication
Event	International Conference on Miniaturized Systems for Chemistry and Life Sciences - Gyeongju, Korea, Republic of Duration: 25 Oct 2015 → 29 Oct 2015 Conference number: 19

Publication series

Name
ISSN (Electronic)	1556-5904

Conference

Conference	International Conference on Miniaturized Systems for Chemistry and Life Sciences
Abbreviated title	MicroTAS
Country/Territory	Korea, Republic of
City	Gyeongju
Period	25/10/2015 → 29/10/2015

Keywords

Electrospray ionization
Mass spectrometry
Microchip electrophoresis
Thiol-ene

Cite this

@inproceedings{956014bbef934702853b411b82f51f43,

title = "Fabrication of thiol-ene based electrophoresis chips with fully integrated electrospray ionization emitter by replication",

abstract = "In this paper, for the first time, we report fabrication of free-standing (no carrier wafer) electrospray ionization (ESI) emitter tips as integral parts of thiol-ene-based electrophoresis chips. Integrated ESI tips enable their direct coupling to mass spectrometry (MS). In addition, we present performance characterization of the developed chips in ESI/MS analysis of peptides and small drug molecules.",

keywords = "Electrospray ionization, Mass spectrometry, Microchip electrophoresis, Thiol-ene",

author = "Sari T{\"a}hk{\"a} and Ashkan Bonabi and Ville Jokinen and Tiina Sikanen",

year = "2015",

language = "English",

publisher = "Chemical and Biological Microsystems Society (CBMS)",

pages = "1758--1760",

booktitle = "MicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences",

address = "United States",

note = "International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS ; Conference date: 25-10-2015 Through 29-10-2015",

}

Tähkä, S, Bonabi, A, Jokinen, V & Sikanen, T 2015, Fabrication of thiol-ene based electrophoresis chips with fully integrated electrospray ionization emitter by replication. in MicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Chemical and Biological Microsystems Society (CBMS), pp. 1758-1760, International Conference on Miniaturized Systems for Chemistry and Life Sciences, Gyeongju, Korea, Republic of, 25/10/2015.

Fabrication of thiol-ene based electrophoresis chips with fully integrated electrospray ionization emitter by replication. / Tähkä, Sari; Bonabi, Ashkan; Jokinen, Ville et al.
MicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Chemical and Biological Microsystems Society (CBMS), 2015. p. 1758-1760.

Research output: Chapter in Book/Report/Conference proceeding › Conference article in proceedings › Scientific › peer-review

TY - GEN

T1 - Fabrication of thiol-ene based electrophoresis chips with fully integrated electrospray ionization emitter by replication

AU - Tähkä, Sari

AU - Bonabi, Ashkan

AU - Jokinen, Ville

AU - Sikanen, Tiina

N1 - Conference code: 19

PY - 2015

Y1 - 2015

N2 - In this paper, for the first time, we report fabrication of free-standing (no carrier wafer) electrospray ionization (ESI) emitter tips as integral parts of thiol-ene-based electrophoresis chips. Integrated ESI tips enable their direct coupling to mass spectrometry (MS). In addition, we present performance characterization of the developed chips in ESI/MS analysis of peptides and small drug molecules.

AB - In this paper, for the first time, we report fabrication of free-standing (no carrier wafer) electrospray ionization (ESI) emitter tips as integral parts of thiol-ene-based electrophoresis chips. Integrated ESI tips enable their direct coupling to mass spectrometry (MS). In addition, we present performance characterization of the developed chips in ESI/MS analysis of peptides and small drug molecules.

KW - Electrospray ionization

KW - Mass spectrometry

KW - Microchip electrophoresis

KW - Thiol-ene

UR - https://www.scopus.com/pages/publications/84983320360

M3 - Conference article in proceedings

SP - 1758

EP - 1760

BT - MicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences

PB - Chemical and Biological Microsystems Society (CBMS)

T2 - International Conference on Miniaturized Systems for Chemistry and Life Sciences

Y2 - 25 October 2015 through 29 October 2015

ER -

Fabrication of thiol-ene based electrophoresis chips with fully integrated electrospray ionization emitter by replication

Abstract

Publication series

Conference

Keywords

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Cite this

Fabrication of thiol-ene based electrophoresis chips with fully integrated electrospray ionization emitter by replication

Abstract

Publication series

Conference

Keywords

Other files and links

Fingerprint

Equipment

Raw Materials Research Infrastructure

Cite this