Exploring epistaxis as an adverse effect of anti-thrombotic drugs and outdoor temperature

Research output: Chapter in Book/Report/Conference proceedingConference contributionScientificpeer-review

Researchers

  • Jaakko Hollmen

  • Henrik Boström
  • Lars Asker
  • Isak Karlsson
  • Panagiotis Papapetrou
  • Birgitta Norstedt Wikner
  • Inger Ohman

Research units

  • KTH Royal Institute of Technology
  • Stockholm University
  • Karolinska Institutet

Abstract

Electronic health records contain a wealth of epidemiological information about diseases at the population level. Using a database of medical diagnoses and drug prescriptions in electronic health records, we investigate the correlation between outdoor temperature and the incidence of epistaxis over time for two groups of patients. One group consists of patients that had been diagnosed with epistaxis and also been prescribed at least one of the three antithrombotic agents: Warfarin, Apixaban, or Rivaroxaban. The other group consists of patients that had been diagnosed with epistaxis and not been prescribed any of the three anti-thrombotic drugs. We find a strong negative correlation between the incidence of epistaxis and outdoor temperature for the group that had not been prescribed any of the three anti-thrombotic drugs, while there is a weaker correlation between incidence of epistaxis and outdoor temperature for the other group. It is, however, clear that both groups are affected in a similar way, such that the incidence of epistaxis increases with colder temperatures.

Details

Original languageEnglish
Title of host publicationProceedings of the 11th PErvasive Technologies Related to Assistive Environments Conference, PETRA 2018
Publication statusPublished - 26 Jun 2018
MoE publication typeA4 Article in a conference publication
EventInternational Conference on Pervasive Technologies Related to Assistive Environments - Corfu, Greece
Duration: 26 Jun 201829 Jun 2018
Conference number: 11

Conference

ConferenceInternational Conference on Pervasive Technologies Related to Assistive Environments
Abbreviated titlePETRA
CountryGreece
CityCorfu
Period26/06/201829/06/2018

    Research areas

  • Adverse drug effects, Correlation, Epistaxis, Regression, Time series

ID: 27180596