Evolution of Structural DNA Nanotechnology

Sami Nummelin, Juhana Kommeri, Mauri A. Kostiainen*, Veikko Linko

*Corresponding author for this work

Research output: Contribution to journalArticleScientificpeer-review

87 Citations (Scopus)
273 Downloads (Pure)


The research field entitled structural DNA nanotechnology emerged in the beginning of the 1980s as the first immobile synthetic nucleic acid junctions were postulated and demonstrated. Since then, the field has taken huge leaps toward advanced applications, especially during the past decade. This Progress Report summarizes how the controllable, custom, and accurate nanostructures have recently evolved together with powerful design and simulation software. Simultaneously they have provided a significant expansion of the shape space of the nanostructures. Today, researchers can select the most suitable fabrication methods, and design paradigms and software from a variety of options when creating unique DNA nanoobjects and shapes for a plethora of implementations in materials science, optics, plasmonics, molecular patterning, and nanomedicine.

Original languageEnglish
Article number1703721
JournalAdvanced Materials
Issue number24
Publication statusPublished - Jun 2018
MoE publication typeA1 Journal article-refereed


  • Computer-aided design
  • Nanotechnology
  • Nucleic acids
  • Programmable materials
  • Self-assembly

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