Engineering Inorganic Materials with DNA Nanostructures

Amelie Heuer-Jungemann*, Veikko Linko

*Corresponding author for this work

Research output: Contribution to journalReview Articlepeer-review

39 Citations (Scopus)
111 Downloads (Pure)


Nucleic acid nanotechnology lays a foundation for the user-friendly design and synthesis of DNA frameworks of any desirable shape with extreme accuracy and addressability. Undoubtedly, such features make these structures ideal modules for positioning and organizing molecules and molecular components into complex assemblies. One of the emerging concepts in the field is to create inorganic and hybrid materials through programmable DNA templates. Here, we discuss the challenges and perspectives of such DNA nanostructure-driven materials science engineering and provide insights into the subject by introducing various DNA-based fabrication techniques including metallization, mineralization, lithography, casting, and hierarchical self-assembly of metal nanoparticles.

Original languageEnglish
Pages (from-to)1969-1979
Number of pages11
JournalACS Central Science
Issue number12
Early online date18 Nov 2021
Publication statusPublished - 22 Dec 2021
MoE publication typeA2 Review article, Literature review, Systematic review


  • nanostructures
  • Metals
  • Genetics
  • Lattices
  • DNA origami


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