Efficient Encapsulation of Fluorinated Drugs in the Confined Space of Water-Dispersible Fluorous Supraparticles

Research output: Contribution to journalArticleScientificpeer-review


  • Claudia Pigliacelli
  • Daniele Maiolo
  • Nonappa Nonappa
  • Johannes Haataja
  • Heinz Amenitsch
  • Claire Michelet
  • Paola Sanchez Moreno
  • Ilaria Tirotta
  • Pierangelo Metrangolo
  • Francesca Baldelli Bombelli

Research units

  • Polytechnic University of Milan
  • Elettra Sincrotrone Trieste


Fluorophobic-driven assemblies of gold nanomaterials were stabilized into water-dispersible fluorous supraparticles by the film-forming protein hydrophobin HFBII. Our strategy makes use of fluorous nanomaterials of different dimensions to engineer size and inner functionalization of the resulting confined space. The inner fluorous compartments allow efficient encapsulation and transport in water of high loadings of partially fluorinated drug molecules.


Original languageEnglish
Pages (from-to)16404–16408
JournalAngewandte Chemie (International Edition)
Issue number51
Early online date6 Nov 2017
Publication statusPublished - 18 Dec 2017
MoE publication typeA1 Journal article-refereed

    Research areas

  • Self-assembly , Supraparticle , Fluorous, Hydrophobin, Gold nanoparticles

ID: 15984966