Effect of 2.45 GHz microwave radiation on the fertility pattern in male mice

Chhoteylal Jonwal, Rashmi Sisodia*, Virender K. Saxena, Kavindra K. Kesari

*Corresponding author for this work

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

A number of studies have reported that male reproductive organs are susceptible to electromagnetic fields (EMFs). The aim of this study was to explore the effects of microwave radiation exposures on 6-8 weeks old male Swiss albino mice. Mice were divided into two groups: group I - sham-exposed (Control), and group II - microwaves-exposed (MWs). Mice were exposed to 2.45 GHz with power density 0.25 mW/cm2, specific absorbtion rate (SAR) 0.09 W/kg. Exposure was given in Plexiglas cages for 2 h/day for 30 days. Results showed that 2.45 GHz microwave radiation resulted in a significant increase (p < 0.001) in catalase (CAT), malondialdehyde (MDA), reactive oxygen species (ROS) and decrease (p < 0.001) in the levels of glutathione peroxidase (GPx), testosterone and superoxide dismutase (SOD) (p < 0.05). Flow cytometer analysis of blood showed the formation of micronuclei in microwave-exposed group. Histopathological changes were also seen in seminiferous tubules of microwave-exposed group as compared to the sham-exposed group. It is concluded that 2.45 GHz microwave radiation exposure causes oxidative stress in testes and it may lead to detrimental and injurious effects on fertility potential of the male reproductive system of Swiss albino mice.

Original languageEnglish
Pages (from-to)453-460
Number of pages8
JournalGeneral Physiology and Biophysics
Volume37
Issue number4
DOIs
Publication statusPublished - 1 Jan 2018
MoE publication typeA1 Journal article-refereed

Keywords

  • Male infertility
  • Micronuclei
  • Microwave radiation
  • Reactive oxygen species
  • Testosterone

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