Abstract
The filamentous fungus, Trichoderma reesei produces all of the enzymatic activities required for efficient hydrolysis of highly ordered crystalline cellulose. All the principal enzymes involved in cellulose hydrolysis possess two functional domains, one directly involved in catalysis and the other in substrate recognition and binding. The availability of high-resolution three dimensional structures of the two domains allows genetic engineering to be used for detailed structure-function studies of these important enzymes.
Original language | English |
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Pages (from-to) | 169-176 |
Number of pages | 8 |
Journal | Journal of Biotechnology |
Volume | 24 |
Issue number | 2 |
Publication status | Published - 15 Jun 1992 |
MoE publication type | A1 Journal article-refereed |
Event | International Conference on the Industrial Applications of Natural, Modified and Artificial Enzymes - Pisa, Italy Duration: 23 Sept 1990 → 29 Sept 1990 |
Keywords
- CELLULASE
- TRICHODERMA
- DOMAINS
- CATALYSIS
- SUBSTRATE BINDING
- CELLULOLYTIC SYSTEM
- LIMITED PROTEOLYSIS
- ENDOGLUCANASE
- GENE
- SYNERGISM
- SEQUENCE
- QM-9414
- ENZYME