Do sparse brain activity patterns underlie human cognition?

Iiro P. Jääskeläinen*, Enrico Glerean, Vasily Klucharev, Anna Shestakova, Jyrki Ahveninen

*Corresponding author for this work

Research output: Contribution to journalComment/debateScientificpeer-review

2 Citations (Scopus)
29 Downloads (Pure)

Abstract

Accumulating multivariate pattern analysis (MVPA) results from fMRI studies suggest that information is represented in fingerprint patterns of activations and deactivations during perception, emotions, and cognition. We postulate that these fingerprint patterns might reflect neuronal-population level sparse code documented in two-photon calcium imaging studies in animal models, i.e., information represented in specific and reproducible ensembles of a few percent of active neurons amidst widespread inhibition in neural populations. We suggest that such representations constitute a fundamental organizational principle via interacting across multiple levels of brain hierarchy, thus giving rise to perception, emotions, and cognition.

Original languageEnglish
Article number119633
Pages (from-to)1-4
Number of pages4
JournalNeuroImage
Volume263
DOIs
Publication statusPublished - Nov 2022
MoE publication typeB1 Non-refereed journal articles

Keywords

  • Cognition
  • Emotions
  • fMRI
  • MVPA
  • Perception
  • Sparse distributed representations

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