Projects per year
Abstract
Structural DNA nanotechnology provides a viable route for building from the bottom-up using DNA as construction material. The most common DNA nanofabrication technique is called DNA origami, and it allows high-throughput synthesis of accurate and highly versatile structures with nanometer-level precision. Here, it is shown how the spatial information of DNA origami can be transferred to metallic nanostructures by combining the bottom-up DNA origami with the conventionally used top-down lithography approaches. This allows fabrication of billions of tiny nanostructures in one step onto selected substrates. The method is demonstrated using bowtie DNA origami to create metallic bowtie-shaped antenna structures on silicon nitride or sapphire substrates. The method relies on the selective growth of a silicon oxide layer on top of the origami deposition substrate, thus resulting in a patterning mask for following lithographic steps. These nanostructure-equipped surfaces can be further used as molecular sensors (e.g., surface-enhanced Raman spectroscopy (SERS)) and in various other optical applications at the visible wavelength range owing to the small feature sizes (sub-10 nm). The technique can be extended to other materials through methodological modifications; therefore, the resulting optically active surfaces may find use in development of metamaterials and metasurfaces.
Original language | English |
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Article number | e60313 |
Journal | Journal of Visualized Experiments |
Issue number | 151 |
DOIs | |
Publication status | Published - 27 Sept 2019 |
MoE publication type | A1 Journal article-refereed |
Fingerprint
Dive into the research topics of 'DNA Origami-Mediated Substrate Nanopatterning of Inorganic Structures for Sensing Applications'. Together they form a unique fingerprint.Projects
- 3 Finished
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SYNVIRO: Synthetic Virology Toolbox for the Encapsulation of Therapeutic Polyelectrolytes (SYNVIRO)
Kostiainen, M. (Principal investigator)
01/09/2017 → 31/08/2021
Project: Academy of Finland: Other research funding
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Protein Cage Directed Self-Assembly of Nanomaterials
Kostiainen, M. (Principal investigator)
01/09/2016 → 31/08/2018
Project: Academy of Finland: Other research funding
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Rationally designed molecular devices through nucleic acid nanotechnology
Linko, V. (Principal investigator)
01/09/2015 → 31/08/2018
Project: Academy of Finland: Other research funding
Equipment
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Bioeconomy Research Infrastructure
Seppälä, J. (Manager)
School of Chemical EngineeringFacility/equipment: Facility
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OtaNano - Nanomicroscopy Center
Seitsonen, J. (Manager) & Rissanen, A. (Other)
OtaNanoFacility/equipment: Facility