DNA origami design and implementation: the Romanian map

Laura Ioana Popa; Ana-Maria Dobre; Corina Itcus; Alexandru Amarioarei; Andrei Paun; Mihaela Paun; Felician Pop; Iris Tusa; Kha Minh-Kha Nguyen; Anton Kuzyk; Eugen Czeizler

doi:10.25083/rbl/25.4/1816.1822

DNA origami design and implementation: the Romanian map

Laura Ioana Popa, Ana-Maria Dobre, Corina Itcus^*, Alexandru Amarioarei, Andrei Paun, Mihaela Paun, Felician Pop, Iris Tusa, Minh-Kha Nguyen, Anton Kuzyk, Eugen Czeizler

^*Corresponding author for this work

Department of Neuroscience and Biomedical Engineering

Research output: Contribution to journal › Article › Scientific › peer-review

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Abstract

Since its introduction in the early 2000s, DNA origami had a big impact on the development of nanotechnology by gathering numerous applications. During this time, many tools were designed and used to generate arbitrary shapes capable of self-assembly which make this technique more approachable. In this paper, we have created the map of Romania at nanoscale dimensions by using a new open-source software - PERDIX. For this purpose, we used a scaffold strand with a length of 6959 nucleotides and 162 staple strands with a variable length ranging between 20 and 63 nucleotides. All the computational tools that were used in this experiment are open-source and user-friendly.

Original language	English
Pages (from-to)	1816-1822
Number of pages	7
Journal	Romanian Biotechnology Letters
Volume	25
Issue number	4
DOIs	https://doi.org/10.25083/rbl/25.4/1816.1822
Publication status	Published - 2020
MoE publication type	A1 Journal article-refereed

Funding

This work was supported by a grant of the Romanian National Authority for Scientific Research and Innovation, project number POC P-37-257.

Keywords

DNA origami
nanotechnology
nanostructure
DNA Romanian map
Perdix visualization
FOLDING DNA
NANOSCALE
SHAPES

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10.25083/rbl/25.4/1816.1822

DNA_Origami_Design.19Final published version, 620 KBLicence: CC BY-NC-ND

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Cite this

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title = "DNA origami design and implementation: the Romanian map",

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TY - JOUR

T1 - DNA origami design and implementation

T2 - the Romanian map

AU - Popa, Laura Ioana

AU - Dobre, Ana-Maria

AU - Itcus, Corina

AU - Amarioarei, Alexandru

AU - Paun, Andrei

AU - Paun, Mihaela

AU - Pop, Felician

AU - Tusa, Iris

AU - Minh-Kha Nguyen, null

AU - Kuzyk, Anton

AU - Czeizler, Eugen

PY - 2020

Y1 - 2020

N2 - Since its introduction in the early 2000s, DNA origami had a big impact on the development of nanotechnology by gathering numerous applications. During this time, many tools were designed and used to generate arbitrary shapes capable of self-assembly which make this technique more approachable. In this paper, we have created the map of Romania at nanoscale dimensions by using a new open-source software - PERDIX. For this purpose, we used a scaffold strand with a length of 6959 nucleotides and 162 staple strands with a variable length ranging between 20 and 63 nucleotides. All the computational tools that were used in this experiment are open-source and user-friendly.

AB - Since its introduction in the early 2000s, DNA origami had a big impact on the development of nanotechnology by gathering numerous applications. During this time, many tools were designed and used to generate arbitrary shapes capable of self-assembly which make this technique more approachable. In this paper, we have created the map of Romania at nanoscale dimensions by using a new open-source software - PERDIX. For this purpose, we used a scaffold strand with a length of 6959 nucleotides and 162 staple strands with a variable length ranging between 20 and 63 nucleotides. All the computational tools that were used in this experiment are open-source and user-friendly.

KW - DNA origami

KW - nanotechnology

KW - nanostructure

KW - DNA Romanian map

KW - Perdix visualization

KW - FOLDING DNA

KW - NANOSCALE

KW - SHAPES

U2 - 10.25083/rbl/25.4/1816.1822

DO - 10.25083/rbl/25.4/1816.1822

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DNA origami design and implementation: the Romanian map

Abstract

Funding

Keywords

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