DNA origami-based nanoribbons: Assembly, length distribution, and twist

Ralf Jungmann*, Max Scheible, Anton Kuzyk, Günther Pardatscher, Carlos E. Castro, Friedrich C. Simmel

*Corresponding author for this work

Research output: Contribution to journalArticleScientificpeer-review

44 Citations (Scopus)

Abstract

A variety of polymerization methods for the assembly of elongated nanoribbons from rectangular DNA origami structures are investigated. The most efficient method utilizes single-stranded DNA oligonucleotides to bridge an intermolecular scaffold seam between origami monomers. This approach allows the fabrication of origami ribbons with lengths of several micrometers, which can be used for long-range ordered arrangement of proteins. It is quantitatively shown that the length distribution of origami ribbons obtained with this technique follows the theoretical prediction for a simple linear polymerization reaction. The design of flat single layer origami structures with constant crossover spacing inevitably results in local underwinding of the DNA helix, which leads to a global twist of the origami structures that also translates to the nanoribbons.

Original languageEnglish
Article number275301
Number of pages6
JournalNanotechnology
Volume22
Issue number27
DOIs
Publication statusPublished - 8 Jul 2011
MoE publication typeA1 Journal article-refereed

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