Diastereoselective Synthesis of Vicinal Amino Alcohols

Oskari Karjalainen; Ari Koskinen

doi:10.1039/C2OB25357G

Diastereoselective Synthesis of Vicinal Amino Alcohols

Oskari Karjalainen
, Ari Koskinen

Research output: Contribution to journal › Article › Scientific › peer-review

167 Citations (Scopus)

551 Downloads (Pure)

Abstract

The vicinal amino alcohol is a common motif in natural products and pharmaceuticals. Amino acids constitute a natural, inexpensive, and enantiopure choice of starting material for the synthesis of such functionalities. However, the matters concerning diastereoselectivity are not obvious. This Perspective takes a look in the field of diastereoselective synthesis of vicinal amino alcohols starting from amino acids using various methods.

Original language	English
Pages (from-to)	43114326
Journal	Organic and Biomolecular Chemistry
Issue number	10
DOIs	https://doi.org/10.1039/C2OB25357G
Publication status	Published - 2012
MoE publication type	A1 Journal article-refereed

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Diastereoselective synthesis of vicinal amino alcoholsAccepted author manuscript, 639 KB

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abstract = "The vicinal amino alcohol is a common motif in natural products and pharmaceuticals. Amino acids constitute a natural, inexpensive, and enantiopure choice of starting material for the synthesis of such functionalities. However, the matters concerning diastereoselectivity are not obvious. This Perspective takes a look in the field of diastereoselective synthesis of vicinal amino alcohols starting from amino acids using various methods.",

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AB - The vicinal amino alcohol is a common motif in natural products and pharmaceuticals. Amino acids constitute a natural, inexpensive, and enantiopure choice of starting material for the synthesis of such functionalities. However, the matters concerning diastereoselectivity are not obvious. This Perspective takes a look in the field of diastereoselective synthesis of vicinal amino alcohols starting from amino acids using various methods.

U2 - 10.1039/C2OB25357G

DO - 10.1039/C2OB25357G

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SP - 43114326

JO - Organic and Biomolecular Chemistry

JF - Organic and Biomolecular Chemistry

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Diastereoselective Synthesis of Vicinal Amino Alcohols

Abstract

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