Diastereoselective Synthesis of Vicinal Amino Alcohols

Oskari Karjalainen; Ari Koskinen

doi:10.1039/C2OB25357G

Diastereoselective Synthesis of Vicinal Amino Alcohols

Oskari Karjalainen, Ari Koskinen

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Abstract

The vicinal amino alcohol is a common motif in natural products and pharmaceuticals. Amino acids constitute a natural, inexpensive, and enantiopure choice of starting material for the synthesis of such functionalities. However, the matters concerning diastereoselectivity are not obvious. This Perspective takes a look in the field of diastereoselective synthesis of vicinal amino alcohols starting from amino acids using various methods.

Original language	English
Pages (from-to)	43114326
Journal	ORGANIC AND BIOMOLECULAR CHEMISTRY
Issue number	10
DOIs	https://doi.org/10.1039/C2OB25357G
Publication status	Published - 2012
MoE publication type	A1 Journal article-refereed

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abstract = "The vicinal amino alcohol is a common motif in natural products and pharmaceuticals. Amino acids constitute a natural, inexpensive, and enantiopure choice of starting material for the synthesis of such functionalities. However, the matters concerning diastereoselectivity are not obvious. This Perspective takes a look in the field of diastereoselective synthesis of vicinal amino alcohols starting from amino acids using various methods.",

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