Development of Polyvinyl Alcohol Based High Strength Biocompatible Composite Films

Amit Kumar Sonker; Arun Kumar Teotia; Ashok Kumar; Rajaram Krishna Nagarale; Vivek Verma

doi:10.1002/macp.201700130

Development of Polyvinyl Alcohol Based High Strength Biocompatible Composite Films

Amit Kumar Sonker, Arun Kumar Teotia, Ashok Kumar, Rajaram Krishna Nagarale, Vivek Verma^*

^*Corresponding author for this work

Not published at Aalto University

Research output: Contribution to journal › Article › Scientific › peer-review

Abstract

In the present work, the development of high strength biocompatible polyvinyl alcohol (PVA) based composite films using citric acid (CA) as a crosslinker and bacterial cellulose nanowhiskers (BCNW) as nanofiller is reported. The interfacial binding between nanoreinforcement (BCNW) and polymer (PVA) is modified by covalently binding them by citric acid. These composite films demonstrate a highest tensile strength of 132 MPa in comparison to PVA (37 MPa). The composite also shows 10‐fold reduction in water swelling percentage and better thermal properties compared to PVA. Hemocompatibility and biocompatibility assays show that the developed high strength composite is nontoxic to blood and is favorable for cell growth. With the aforementioned strength and biocompatibility, the composite for development for bioimplants is proposed.

Original language	English
Article number	1700130
Number of pages	13
Journal	Macromolecular Chemistry and Physics
Volume	218
Issue number	15
Early online date	24 May 2017
DOIs	https://doi.org/10.1002/macp.201700130
Publication status	Published - Aug 2017
MoE publication type	A1 Journal article-refereed

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title = "Development of Polyvinyl Alcohol Based High Strength Biocompatible Composite Films",

abstract = "In the present work, the development of high strength biocompatible polyvinyl alcohol (PVA) based composite films using citric acid (CA) as a crosslinker and bacterial cellulose nanowhiskers (BCNW) as nanofiller is reported. The interfacial binding between nanoreinforcement (BCNW) and polymer (PVA) is modified by covalently binding them by citric acid. These composite films demonstrate a highest tensile strength of 132 MPa in comparison to PVA (37 MPa). The composite also shows 10‐fold reduction in water swelling percentage and better thermal properties compared to PVA. Hemocompatibility and biocompatibility assays show that the developed high strength composite is nontoxic to blood and is favorable for cell growth. With the aforementioned strength and biocompatibility, the composite for development for bioimplants is proposed.",

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AU - Sonker, Amit Kumar

AU - Teotia, Arun Kumar

AU - Kumar, Ashok

AU - Nagarale, Rajaram Krishna

AU - Verma, Vivek

PY - 2017/8

Y1 - 2017/8

N2 - In the present work, the development of high strength biocompatible polyvinyl alcohol (PVA) based composite films using citric acid (CA) as a crosslinker and bacterial cellulose nanowhiskers (BCNW) as nanofiller is reported. The interfacial binding between nanoreinforcement (BCNW) and polymer (PVA) is modified by covalently binding them by citric acid. These composite films demonstrate a highest tensile strength of 132 MPa in comparison to PVA (37 MPa). The composite also shows 10‐fold reduction in water swelling percentage and better thermal properties compared to PVA. Hemocompatibility and biocompatibility assays show that the developed high strength composite is nontoxic to blood and is favorable for cell growth. With the aforementioned strength and biocompatibility, the composite for development for bioimplants is proposed.

AB - In the present work, the development of high strength biocompatible polyvinyl alcohol (PVA) based composite films using citric acid (CA) as a crosslinker and bacterial cellulose nanowhiskers (BCNW) as nanofiller is reported. The interfacial binding between nanoreinforcement (BCNW) and polymer (PVA) is modified by covalently binding them by citric acid. These composite films demonstrate a highest tensile strength of 132 MPa in comparison to PVA (37 MPa). The composite also shows 10‐fold reduction in water swelling percentage and better thermal properties compared to PVA. Hemocompatibility and biocompatibility assays show that the developed high strength composite is nontoxic to blood and is favorable for cell growth. With the aforementioned strength and biocompatibility, the composite for development for bioimplants is proposed.

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DO - 10.1002/macp.201700130

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JO - Macromolecular Chemistry and Physics

JF - Macromolecular Chemistry and Physics

SN - 1022-1352

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Development of Polyvinyl Alcohol Based High Strength Biocompatible Composite Films

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