Determination of particle size distribution and analysis of a natural food supplement on pectin base

Svetla Dyankova, Maria Doneva, Yancho Todorov, Margarita Terziyska

Research output: Contribution to journalArticleScientificpeer-review

Abstract

The pectin is among the most studied soluble dietary fiber with cholesterol lowering properties. The major difficulty in its use is the slow dissolution and the lumps formation when placed in water. The main objective of this research is through technological methods to achieve a more rapid and complete dissolution of high-esterified citrus pectin in water. The method used is wet granulation with different granulation liquids (sucrose solution, distilled water and water-ethanol mixtures) and the resulting variant granules are tested for particle size distribution, solubility and hydration rate. Granulation of high-methoxyl citrus pectin improves its dissolution in water in comparison with the powder pectin. Also, the hydration rate at the 300th s is greater than 90% with the granulated pectin and only 54% with non-granulated. Among the obtained five variants of granules, the best results are observed in the variant, granulated with 40% (v/v) ethanol. The analysis of the size and distribution of the particles reports the least scattering of the results during the variants granulated with 25% and 40% ethanol, which corresponds to the highest degree of uniformity of the granules.
Original languageEnglish
Pages (from-to)1
Number of pages8
JournalIOSR Journal Of Pharmacy
Volume6
Issue number5
Publication statusPublished - May 2016
MoE publication typeA1 Journal article-refereed

Keywords

  • dissolution
  • dissolution, granulation, particle size distribution
  • modeling
  • statistics

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