Design methods for 3D wireframe DNA nanostructures

Pekka Orponen*

*Corresponding author for this work

Research output: Contribution to journalArticleScientificpeer-review

6 Citations (Scopus)
120 Downloads (Pure)

Abstract

The field of structural DNA nanotechnology aims at the systematic development of self-assembling nanostructures using DNA as the construction material. Research in this area is progressing rapidly, and the controlled, computer-aided design of increasingly complex structures is becoming feasible. One thread of this endeavour is the design and characterisation of self-assembling 3D nanostructures based on wireframe polyhedral models. This article aims to illustrate some of the key developments in this direction, in sufficient detail so that the reader can achieve a general understanding of the main concepts and approaches. The emphasis is on the design principles rather than experimental methodology, and the role of computer science and computational tools is set forth.

Original languageEnglish
Pages (from-to)147-160
JournalNatural Computing
Volume17
Issue number1
Early online date2017
DOIs
Publication statusPublished - Mar 2018
MoE publication typeA1 Journal article-refereed

Keywords

  • 3D nanostructures
  • DNA nanotechnology
  • DNA origami
  • Self-assembly
  • Wireframe models

Fingerprint Dive into the research topics of 'Design methods for 3D wireframe DNA nanostructures'. Together they form a unique fingerprint.

  • Projects

    ALBION: Algorithmic Designs for Biomolecular Nanostructures (ALBION)

    Mohammed, A., Orponen, P., Saman Booy, M., Vo, T., Lohikko, A., Elonen, A. & Korpela, D.

    01/09/201731/08/2021

    Project: Academy of Finland: Other research funding

    Cite this