TY - JOUR
T1 - Deriving stair-climbing performance outcome measures using the smartphone barometer
T2 - Results of an algorithm development study
AU - Tengström, Mette
AU - Byrom, Bill
AU - Volotinen, Sami
AU - Huopaniemi, Ulla
AU - Laurila, Tomi
N1 - Publisher Copyright:
© 2022 Elsevier Inc.
PY - 2022/9
Y1 - 2022/9
N2 - As we seek to gain richer insights to understand intervention effects, and increasingly decentralise aspects of clinical trials to simplify participation, there is a growing interest in leveraging wearables and sensors to generate novel and informative clinical outcome measures for at-home assessment. The sensors embedded within smartphone technology provide one approach to capture of this data, and may be particularly useful when patients are already using mobile devices for at-home capture of other clinical trials data, such as patient-reported outcomes. We describe the results of an initial algorithm development study to determine whether the atmospheric pressure data provided by an onboard smartphone sensor is sufficiently informative to enable detection of a small height gain, such as that achieved during a short stair climb performance test. We were able to sufficiently distinguish height changes of 0.6 m in indoor conditions, representing around 4 stairs on an average staircase. This suggests that the smartphone barometer may indeed be suitable for inclusion within future work developing a stair-climbing performance outcome test instrumented using a mobile application.
AB - As we seek to gain richer insights to understand intervention effects, and increasingly decentralise aspects of clinical trials to simplify participation, there is a growing interest in leveraging wearables and sensors to generate novel and informative clinical outcome measures for at-home assessment. The sensors embedded within smartphone technology provide one approach to capture of this data, and may be particularly useful when patients are already using mobile devices for at-home capture of other clinical trials data, such as patient-reported outcomes. We describe the results of an initial algorithm development study to determine whether the atmospheric pressure data provided by an onboard smartphone sensor is sufficiently informative to enable detection of a small height gain, such as that achieved during a short stair climb performance test. We were able to sufficiently distinguish height changes of 0.6 m in indoor conditions, representing around 4 stairs on an average staircase. This suggests that the smartphone barometer may indeed be suitable for inclusion within future work developing a stair-climbing performance outcome test instrumented using a mobile application.
KW - Clinical outcome assessments
KW - Performance outcomes
KW - Remote assessments
KW - Smartphone barometer
KW - Stair-climb tests
UR - http://www.scopus.com/inward/record.url?scp=85136909843&partnerID=8YFLogxK
U2 - 10.1016/j.cct.2022.106862
DO - 10.1016/j.cct.2022.106862
M3 - Article
C2 - 35907489
AN - SCOPUS:85136909843
SN - 1551-7144
VL - 120
JO - Contemporary Clinical Trials
JF - Contemporary Clinical Trials
M1 - 106862
ER -