Causal connectivity according to conscious experience in non-rapid eye movement sleep

Minji Lee*, Benjamin Baird, Olivia Gosseries, Jaakko O. Nieminen, Melanie Boly, Giulio Tononi, Seong Whan Lee

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionScientificpeer-review

Abstract

The understanding of human consciousness based on brain connectivity is considered important for brain-machine interfacing. In this study, we investigated changes in causal connectivity in electroencephalography data related to conscious and unconscious experiences during non-rapid eye movement sleep after parietal transcranial magnetic stimulation (TMS). A serial awakening paradigm was used to determine whether subjects had had a conscious experience or not. We calculated direct transfer function (DTF) as a measure of effective connectivity in five frequency bands focusing on frontal and parietal-occipital regions. The DTF showed significant differences in frontal-to-parietal flow between reported unconsciousness and consciousness. During the first 100 ms after TMS, the outward links of the parietal region at low frequencies were higher in no conscious experience than in conscious experience. During the next 100 ms, however, the outward links of the frontal region were higher in the conscious experience than the no conscious experience at low frequencies. Changes with causal connectivity over time after TMS indicate that the spatial roles in brain regions associated with consciousness are different. These findings may help clarify the cortical mechanisms related to conscious experience.

Original languageEnglish
Title of host publication2019 IEEE International Conference on Systems, Man and Cybernetics, SMC 2019
PublisherIEEE
Pages2133-2138
Number of pages6
ISBN (Electronic)9781728145693
DOIs
Publication statusPublished - 1 Oct 2019
MoE publication typeA4 Article in a conference publication
EventIEEE International Conference on Systems, Man, and Cybernetics - Bari, Italy
Duration: 6 Oct 20199 Oct 2019

Publication series

NameConference Proceedings - IEEE International Conference on Systems, Man and Cybernetics
Volume2019-October
ISSN (Print)1062-922X

Conference

ConferenceIEEE International Conference on Systems, Man, and Cybernetics
Abbreviated titleSMC
CountryItaly
CityBari
Period06/10/201909/10/2019

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  • Cite this

    Lee, M., Baird, B., Gosseries, O., Nieminen, J. O., Boly, M., Tononi, G., & Lee, S. W. (2019). Causal connectivity according to conscious experience in non-rapid eye movement sleep. In 2019 IEEE International Conference on Systems, Man and Cybernetics, SMC 2019 (pp. 2133-2138). [8914541] (Conference Proceedings - IEEE International Conference on Systems, Man and Cybernetics; Vol. 2019-October). IEEE. https://doi.org/10.1109/SMC.2019.8914541