Biomolecule-Directed Carbon Nanotube Self-Assembly

Eduardo Anaya-Plaza*, Ahmed Shaukat, Inka Lehtonen, Mauri A. Kostiainen

*Corresponding author for this work

Research output: Contribution to journalReview Articlepeer-review

27 Citations (Scopus)
128 Downloads (Pure)


The strategy of combining biomolecules and synthetic components to develop biohybrids is becoming increasingly popular for preparing highly customized and biocompatible functional materials. Carbon nanotubes (CNTs) benefit from bioconjugation, allowing their excellent properties to be applied to biomedical applications. This study reviews the state-of-the-art research in biomolecule–CNT conjugates and discusses strategies for their self-assembly into hierarchical structures. The review focuses on various highly ordered structures and the interesting properties resulting from the structural order. Hence, CNTs conjugated with the most relevant biomolecules, such as nucleic acids, peptides, proteins, saccharides, and lipids are discussed. The resulting well-defined composites allow the nanoscale properties of the CNTs to be exploited at the micro- and macroscale, with potential applications in tissue engineering, sensors, and wearable electronics. This review presents the underlying chemistry behind the CNT-based biohybrid materials and discusses the future directions of the field.

Original languageEnglish
Article number2001162
Number of pages17
JournalAdvanced Healthcare Materials
Issue number1
Early online date29 Oct 2020
Publication statusPublished - 6 Jan 2021
MoE publication typeA2 Review article, Literature review, Systematic review


  • bioapplications
  • biomolecules
  • carbon nanotubes
  • nanomaterials
  • self-assembly


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