Bioinduced room temperature methanol reforming

L.E. Heim, Daniel Thiel, C. Gedig, Jan Deska, M.H.G. Prechtl

Research output: Contribution to journalArticleScientificpeer-review

44 Citations (Scopus)
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Imitating Nature's approach in nucleophile-activated formaldehyde dehydrogenation, air stable ruthenium complexes proved to be exquisite catalysts for the dehydrogenation of formaldehyde hydrate as well as for the transfer hydrogenation to unsaturated organic substrates at loadings as low as 0.5 mol%. Concatenation of the chemical hydrogen fixation route with an oxidase-mediated activation of methanol renders an artificial methylotrophic in vitro metabolism providing methanol-derived reduction equivalents for synthetic hydrogenation purposes. Moreover, for the first time methanol reforming at room temperature was achieved on the basis of this bioinduced dehydrogenation path delivering hydrogen gas from aqueous methanol.
Original languageEnglish
Pages (from-to)10308-10312
JournalAngewandte Chemie - International Edition
Issue number35
Publication statusPublished - 2015
MoE publication typeA1 Journal article-refereed


  • hydrogen formation
  • bioinspired
  • chemoenzymatic
  • biocatalysis
  • ruthenium


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