Abstract
A novel biofunctionalized nanofibrous membrane is developed through immobilization of protein ligands on the surface of nanofibers. The biofunctionalization not only enhances the membrane's structural properties including mechanical and thermal ones but also makes the membrane capable to separate nanoparticles and biomolecules much smaller than the pore size from water efficiently. Upon contact with water, the conformational change of the protein immobilized leads to its swelling, thereby an enlarged functional surface area and a higher steric hindrance capturing the filtrates. In case of filtration of a plasmonic nanoparticle containing suspension, decoration of the membrane with the plasmonic nanoparticles forms a smart bionanocomposite biosensor for detection of protein denaturation.
| Original language | English |
|---|---|
| Pages (from-to) | 186-193 |
| Number of pages | 8 |
| Journal | Bioinspired, Biomimetic and Nanobiomaterials |
| Volume | 2 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - 2013 |
| MoE publication type | A1 Journal article-refereed |
Funding
M Elbahri thanks the initiative and networking fund of the Helmholtz Associations for providing the financial base of the start-up of his research group. The authors gratefully acknowledge the partial financial support by the German Research Foundation (DFG) through the projects SFB 677 C9. Stefan Rehders for drawing the sketches, and Dr. Rania Khalil and Ramzy Abdelaziz for their valuable cooperation in the experimental part are also acknowledged. The authors would like also to appreciate Silvio Neumann for TGA and DSC measurements, Heinrich Bottcher for tensile tests and Karen-Marita Prause for SEM measurements.
Keywords
- biomimetic materials
- functional nanomaterials
- membranes
- polymer functionalization
- protein
- GOLD NANOPARTICLES
- FILTRATION
- PREFILTERS
- RESONANCES
- RESISTANT
- PROTEINS
- WATER
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