Benchmarking for On-Scalp MEG Sensors

Minshu Xie, Justin F. Schneiderman*, Maxim L. Chukharkin, Alexei Kalabukhov, Bushra Riaz, Daniel Lundqvist, Stephen Whitmarsh, Matti Hämäläinen, Veikko Jousmäki, Robert Oostenveld, Dag Winkler

*Corresponding author for this work

Research output: Contribution to journalArticleScientificpeer-review

11 Citations (Scopus)

Abstract

Objective: We present a benchmarking protocol for quantitatively comparing emerging on-scalp magnetoencephalography (MEG) sensor technologies to their counterparts in state-of-the-art MEG systems. Methods: As a means of validation, we compare a high-critical-temperature superconducting quantum interference device (high T-c SQUID) with the low-T-c SQUIDs of an Elekta Neuromag TRIUX system in MEG recordings of auditory and somatosensory evoked fields (SEFs) on one human subject. Results: We measure the expected signal gain for the auditory-evoked fields (deeper sources) and notice some unfamiliar features in the on-scalp sensor-based recordings of SEFs (shallower sources). Conclusion: The experimental results serve as a proof of principle for the benchmarking protocol. This approach is straightforward, general to various on-scalp MEG sensors, and convenient to use on human subjects. The unexpected features in the SEFs suggest on-scalp MEG sensors may reveal information about neuromagnetic sources that is otherwise difficult to extract from state-of-the-art MEG recordings. Significance: As the first systematically established on-scalp MEG benchmarking protocol, magnetic sensor developers can employ this method to prove the utility of their technology in MEG recordings. Further exploration of the SEFs with on-scalp MEG sensors may reveal unique information about their sources.

Original languageEnglish
Pages (from-to)1270-1276
Number of pages7
JournalIEEE Transactions on Biomedical Engineering
Volume64
Issue number6
DOIs
Publication statusPublished - Jun 2017
MoE publication typeA1 Journal article-refereed

Keywords

  • Auditory and somatosensory evoked fields (AEF and SEF)
  • benchmark
  • high-temperature superconductors
  • magnetoencephalography (MEG)
  • superconducting quantum interference device (SQUID)
  • SYSTEM
  • DIPOLE
  • BRAIN

Cite this

Xie, M., Schneiderman, J. F., Chukharkin, M. L., Kalabukhov, A., Riaz, B., Lundqvist, D., ... Winkler, D. (2017). Benchmarking for On-Scalp MEG Sensors. IEEE Transactions on Biomedical Engineering, 64(6), 1270-1276. https://doi.org/10.1109/TBME.2016.2599177