Auditory representation of learned sound sequences in motor regions of the macaque brain

Denis Archakov, Iain DeWitt, Paweł Kuśmierek, Michael Ortiz-Rios, Daniel Cameron, Ding Cui, Elyse L. Morin, John W. VanMeter, Mikko Sams, Iiro P. Jääskeläinen, Josef P. Rauschecker

Research output: Contribution to journalArticleScientificpeer-review

1 Citation (Scopus)
34 Downloads (Pure)

Abstract

Human speech production requires the ability to couple motor actions with their auditory consequences. Nonhuman primates might not have speech because they lack this ability. To address this question, we trained macaques to perform an auditory-motor task producing sound sequences via hand presses on a newly designed device ("monkey piano"). Catch trials were interspersed to ascertain the monkeys were listening to the sounds they produced. Functional MRI was then used to map brain activity while the animals listened attentively to the sound sequences they had learned to produce and to two control sequences, which were either completely unfamiliar or familiar through passive exposure only. All sounds activated auditory midbrain and cortex, but listening to the sequences that were learned by self-production additionally activated the putamen and the hand and arm regions of motor cortex. These results indicate that, in principle, monkeys are capable of forming internal models linking sound perception and production in motor regions of the brain, so this ability is not special to speech in humans. However, the coupling of sounds and actions in nonhuman primates (and the availability of an internal model supporting it) seems not to extend to the upper vocal tract, that is, the supralaryngeal articulators, which are key for the production of speech sounds in humans. The origin of speech may have required the evolution of a "command apparatus" similar to the control of the hand, which was crucial for the evolution of tool use.

Original languageEnglish
Pages (from-to)15242-15252
Number of pages11
JournalProceedings of the National Academy of Sciences of the United States of America
Volume117
Issue number26
DOIs
Publication statusPublished - 30 Jun 2020
MoE publication typeA1 Journal article-refereed

Keywords

  • auditory cortex
  • internal models
  • motor cortex
  • putamen

Fingerprint Dive into the research topics of 'Auditory representation of learned sound sequences in motor regions of the macaque brain'. Together they form a unique fingerprint.

Cite this