Attenuation correction synthesis for hybrid PET-MR scanners: Application to brain studies

Research output: Contribution to journalArticle

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Attenuation correction synthesis for hybrid PET-MR scanners : Application to brain studies. / Burgos, Ninon; Cardoso, M. Jorge; Thielemans, Kris; Modat, Marc; Pedemonte, Stefano; Dickson, John; Barnes, Anna; Ahmed, Rebekah; Mahoney, Colin J.; Schott, Jonathan M.; Duncan, John S.; Atkinson, David; Arridge, Simon R.; Hutton, Brian F.; Ourselin, Sebastien.

In: IEEE Transactions on Medical Imaging, Vol. 33, No. 12, 6858020, 01.12.2014, p. 2332-2341.

Research output: Contribution to journalArticle

Harvard

Burgos, N, Cardoso, MJ, Thielemans, K, Modat, M, Pedemonte, S, Dickson, J, Barnes, A, Ahmed, R, Mahoney, CJ, Schott, JM, Duncan, JS, Atkinson, D, Arridge, SR, Hutton, BF & Ourselin, S 2014, 'Attenuation correction synthesis for hybrid PET-MR scanners: Application to brain studies', IEEE Transactions on Medical Imaging, vol. 33, no. 12, 6858020, pp. 2332-2341. https://doi.org/10.1109/TMI.2014.2340135

APA

Burgos, N., Cardoso, M. J., Thielemans, K., Modat, M., Pedemonte, S., Dickson, J., ... Ourselin, S. (2014). Attenuation correction synthesis for hybrid PET-MR scanners: Application to brain studies. IEEE Transactions on Medical Imaging, 33(12), 2332-2341. [6858020]. https://doi.org/10.1109/TMI.2014.2340135

Vancouver

Burgos N, Cardoso MJ, Thielemans K, Modat M, Pedemonte S, Dickson J et al. Attenuation correction synthesis for hybrid PET-MR scanners: Application to brain studies. IEEE Transactions on Medical Imaging. 2014 Dec 1;33(12):2332-2341. 6858020. https://doi.org/10.1109/TMI.2014.2340135

Author

Burgos, Ninon ; Cardoso, M. Jorge ; Thielemans, Kris ; Modat, Marc ; Pedemonte, Stefano ; Dickson, John ; Barnes, Anna ; Ahmed, Rebekah ; Mahoney, Colin J. ; Schott, Jonathan M. ; Duncan, John S. ; Atkinson, David ; Arridge, Simon R. ; Hutton, Brian F. ; Ourselin, Sebastien. / Attenuation correction synthesis for hybrid PET-MR scanners : Application to brain studies. In: IEEE Transactions on Medical Imaging. 2014 ; Vol. 33, No. 12. pp. 2332-2341.

Bibtex - Download

@article{00e4abc820be46fda89752cb0639efa9,
title = "Attenuation correction synthesis for hybrid PET-MR scanners: Application to brain studies",
abstract = "Attenuation correction is an essential requirement for quantification of positron emission tomography (PET) data. In PET/CT acquisition systems, attenuation maps are derived from computed tomography (CT) images. However, in hybrid PET/MR scanners, magnetic resonance imaging (MRI) images do not directly provide a patient-specific attenuation map. The aim of the proposed work is to improve attenuation correction for PET/MR scanners by generating synthetic CTs and attenuation maps. The synthetic images are generated through a multi-atlas information propagation scheme, locally matching the MRI-derived patient's morphology to a database of MRI/CT pairs, using a local image similarity measure. Results show significant improvements in CT synthesis and PET reconstruction accuracy when compared to a segmentation method using an ultrashort-echo-time MRI sequence and to a simplified atlas-based method.",
keywords = "Attenuation correction, image synthesis, positron emission tomography/magnetic resonance (PET/MR)",
author = "Ninon Burgos and Cardoso, {M. Jorge} and Kris Thielemans and Marc Modat and Stefano Pedemonte and John Dickson and Anna Barnes and Rebekah Ahmed and Mahoney, {Colin J.} and Schott, {Jonathan M.} and Duncan, {John S.} and David Atkinson and Arridge, {Simon R.} and Hutton, {Brian F.} and Sebastien Ourselin",
year = "2014",
month = "12",
day = "1",
doi = "10.1109/TMI.2014.2340135",
language = "English",
volume = "33",
pages = "2332--2341",
journal = "IEEE Transactions on Medical Imaging",
issn = "0278-0062",
publisher = "IEEE",
number = "12",

}

RIS - Download

TY - JOUR

T1 - Attenuation correction synthesis for hybrid PET-MR scanners

T2 - Application to brain studies

AU - Burgos, Ninon

AU - Cardoso, M. Jorge

AU - Thielemans, Kris

AU - Modat, Marc

AU - Pedemonte, Stefano

AU - Dickson, John

AU - Barnes, Anna

AU - Ahmed, Rebekah

AU - Mahoney, Colin J.

AU - Schott, Jonathan M.

AU - Duncan, John S.

AU - Atkinson, David

AU - Arridge, Simon R.

AU - Hutton, Brian F.

AU - Ourselin, Sebastien

PY - 2014/12/1

Y1 - 2014/12/1

N2 - Attenuation correction is an essential requirement for quantification of positron emission tomography (PET) data. In PET/CT acquisition systems, attenuation maps are derived from computed tomography (CT) images. However, in hybrid PET/MR scanners, magnetic resonance imaging (MRI) images do not directly provide a patient-specific attenuation map. The aim of the proposed work is to improve attenuation correction for PET/MR scanners by generating synthetic CTs and attenuation maps. The synthetic images are generated through a multi-atlas information propagation scheme, locally matching the MRI-derived patient's morphology to a database of MRI/CT pairs, using a local image similarity measure. Results show significant improvements in CT synthesis and PET reconstruction accuracy when compared to a segmentation method using an ultrashort-echo-time MRI sequence and to a simplified atlas-based method.

AB - Attenuation correction is an essential requirement for quantification of positron emission tomography (PET) data. In PET/CT acquisition systems, attenuation maps are derived from computed tomography (CT) images. However, in hybrid PET/MR scanners, magnetic resonance imaging (MRI) images do not directly provide a patient-specific attenuation map. The aim of the proposed work is to improve attenuation correction for PET/MR scanners by generating synthetic CTs and attenuation maps. The synthetic images are generated through a multi-atlas information propagation scheme, locally matching the MRI-derived patient's morphology to a database of MRI/CT pairs, using a local image similarity measure. Results show significant improvements in CT synthesis and PET reconstruction accuracy when compared to a segmentation method using an ultrashort-echo-time MRI sequence and to a simplified atlas-based method.

KW - Attenuation correction

KW - image synthesis

KW - positron emission tomography/magnetic resonance (PET/MR)

UR - http://www.scopus.com/inward/record.url?scp=84914112740&partnerID=8YFLogxK

U2 - 10.1109/TMI.2014.2340135

DO - 10.1109/TMI.2014.2340135

M3 - Article

VL - 33

SP - 2332

EP - 2341

JO - IEEE Transactions on Medical Imaging

JF - IEEE Transactions on Medical Imaging

SN - 0278-0062

IS - 12

M1 - 6858020

ER -

ID: 9014625