Asymmetric organocatalytic Michael addition of Meldrum's acid to nitroalkenes: probing the mechanism of bifunctional thiourea organocatalysts

Research output: Contribution to journalArticleScientificpeer-review


Research units


The asymmetric Michael addition of Meldrum’s acid to nitroalkenes was studied using a novel type of Cinchona alkaloid-based bifunctional thiourea organocatalyst. The functionality of the thiourea catalysts was also probed by preparing and testing thiourea-N-methylated analogues of the well-known bis-(3,5-trifluoromethyl)phenyl-substituted catalyst.


Original languageEnglish
Pages (from-to)205-223
Publication statusPublished - 2010
MoE publication typeA1 Journal article-refereed

    Research areas

  • Asymmetric, organocatalytics, Michael addition, bifunctional thiourea catalysts, cinchona alkaloids, Meldrum's acid

Download statistics

No data available

ID: 959709