Assessing indoor air toxicity with condensate collected from air using the mitochondrial activity of human BJ fibroblasts and THP-1 monocytes

Research output: Contribution to conferencePaperScientificpeer-review

Researchers

Research units

  • Tampere University
  • Daikin North America LLC
  • University of Texas at Austin
  • Tallinn University of Technology

Abstract

The hypothesis for our study was that air and airborne moisture are carriers of possible toxic compounds and these compounds can be collected as condensate using dry ice. Using human cells, we aimed to evaluate the indoor air toxic risk from the condensed water collected from several office and laboratory rooms in two different buildings, both located at the University of Texas at Austin. Condensate samples were collected by using stainless steel collectors (E-collectors), and the effects of samples on the viability of human BJ fibroblast and activated THP-1-monocytes in vitro were investigated by using WST-1 cytotoxicity assays. Toxicological assessment utilizing human BJ fibroblasts and activated THP-1-monocytes of condensate from air reflects the acute toxic effects of the indoor air. The first results suggest that toxicological assessment of condensate collected from air using dry ice in stainless steel condensate collectors and human BJ fibroblasts and activated THP-1-monocytes as test organisms could be useful in detecting indoor air anomalies.

Details

Original languageEnglish
Publication statusPublished - 22 Jul 2018
MoE publication typeNot Eligible
EventConference of the International Society of Indoor Air Quality and Climate - Philadelphia , United States
Duration: 22 Jul 201827 Jul 2018
Conference number: 15
http://www.indoorair2018.org/

Conference

ConferenceConference of the International Society of Indoor Air Quality and Climate
Abbreviated titleISIAQ
CountryUnited States
CityPhiladelphia
Period22/07/201827/07/2018
Internet address

ID: 31186801