Projects per year
Abstract
We proposed a simple method to process hydrogels containing polyvinyl alcohol and cellulose nanofibrils (PVA/CNF) to prepare volumetric architectures by direct ink writing (DIW). The presence of CNF in the aqueous PVA suspensions conferred rheology profiles that were suitable for extrusion and solidification in pre-designed shapes. The viscoelastic behavior of the hybrid inks enabled precise control on processability and shape retention, for instance, as demonstrated in multilayered lattice structures of high fidelity. After lyophilization, the obtained 3D-printed hydrogels presented a very high porosity, with open and interconnected pores, allowing a high-water uptake capacity (up to 1600%). The mechanical strength of the composite 3D-printed materials matched those of soft tissues, opening opportunities for skin applications. As such, drug-loaded samples revealed a controlled and efficient delivery of an antioxidant (ascorbic acid) in PBS buffer media at 23 °C (~80% for 8 h). Altogether, PVA/CNF hydrogels were introduced as suitable precursors of 3D-lattice geometries with excellent physical and mechanical characteristics.
Original language | English |
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Article number | 112424 |
Number of pages | 12 |
Journal | Materials Science and Engineering C |
Volume | 130 |
Early online date | 11 Sept 2021 |
DOIs | |
Publication status | Published - Nov 2021 |
MoE publication type | A1 Journal article-refereed |
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Dive into the research topics of 'Ascorbic acid-loaded polyvinyl alcohol/cellulose nanofibril hydrogels as precursors for 3D printed materials'. Together they form a unique fingerprint.Projects
- 3 Finished
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BIOECONOMY: BIOECONOMY Alliance for excellence in sustainable biomass refining
Seppälä, J. (Principal investigator)
01/01/2020 → 31/12/2023
Project: RCF Research Infrastructure
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VALUEBIOMAT: Bio-oils based polymeric composites; value chain from syntheisis to additive manufacturing
Seppälä, J. (Principal investigator)
01/06/2019 → 28/02/2023
Project: Academy of Finland: Strategic research funding
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3D-manufacturing of novel biomaterials
Seppälä, J. (Principal investigator)
01/01/2017 → 30/06/2021
Project: Academy of Finland: Other research funding
Equipment
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Bioeconomy Research Infrastructure
Seppälä, J. (Manager)
School of Chemical EngineeringFacility/equipment: Facility
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OtaNano - Nanomicroscopy Center
Seitsonen, J. (Manager) & Rissanen, A. (Other)
OtaNanoFacility/equipment: Facility