Airborne toxicity of a non-ionic alcohol ethoxylate surfactant and wetting agent used in cleaning chemicals

Emmanuelle Castagnoli; M.A.  Andersson; Raimo Mikkola; Jarek Kurnitski; Heidi Salonen

Airborne toxicity of a non-ionic alcohol ethoxylate surfactant and wetting agent used in cleaning chemicals

Emmanuelle Castagnoli, M.A. Andersson, Raimo Mikkola, Jarek Kurnitski, Heidi Salonen

Department of Civil Engineering

Tallinn University of Technology

Research output: Chapter in Book/Report/Conference proceeding › Conference article in proceedings › Professional

Abstract

Information on the bioactivity of the surfactants present in cleaning chemicals and their effect on the indoor ecosystems of buildings are needed to provide safe cleaning practices and healthy indoor air. In this study, in vitro (murine neuroblastoma cells and porcine kidney epithelial cells) and ex vivo bioassays (boar sperm) were developed to measure the airborne toxicity of genapol X-080 (polyethylene glycol monoalkyl ethers), used as surfactant and wetting agent in indoor environments. The diffusion and toxicity of airborne genapol X-080 dilutions were demonstrated using two-compartment Petri dishes. Resazurin was also added, to test airborne diffusion of genapol X-080. This preliminary method proved that airborne diffusion of genapol X-080 was possible and toxic toward mammalian cells. Moreover, the ex vivo bioassays were ten times more sensitive. The resazurin + genapol X-080 test showed potential for developing a new and easy method to track the airborne diffusion of polyethylene glycol monoalkyl ethers used in buildings.

Original language	English
Title of host publication	Proceedings Indoor Air 2018: The 15th international conference of Indoor Air quality and Climate Philadelphia, USA, July 22-27 2018
Publisher	International Society for Indoor Air Quality and Climate (ISIAQ)
Number of pages	8
Publication status	Published - Jul 2018
MoE publication type	D3 Professional conference proceedings
Event	Conference of the International Society of Indoor Air Quality and Climate - Philadelphia , United States Duration: 22 Jul 2018 → 27 Jul 2018 Conference number: 15 http://www.indoorair2018.org/

Conference

Conference	Conference of the International Society of Indoor Air Quality and Climate
Abbreviated title	ISIAQ
Country/Territory	United States
City	Philadelphia
Period	22/07/2018 → 27/07/2018
Internet address	http://www.indoorair2018.org/

Keywords

indoor air quality
non-ionic surfactant
genapol X-080
boar spermatozoa
somatic cell lines
Bioassays

Cite this

Castagnoli, E., Andersson, M. A., Mikkola, R., Kurnitski, J., & Salonen, H. (2018). Airborne toxicity of a non-ionic alcohol ethoxylate surfactant and wetting agent used in cleaning chemicals. In Proceedings Indoor Air 2018: The 15th international conference of Indoor Air quality and Climate Philadelphia, USA, July 22-27 2018 Article ID373 International Society for Indoor Air Quality and Climate (ISIAQ).

Castagnoli, Emmanuelle ; Andersson, M.A. ; Mikkola, Raimo et al. / Airborne toxicity of a non-ionic alcohol ethoxylate surfactant and wetting agent used in cleaning chemicals. Proceedings Indoor Air 2018: The 15th international conference of Indoor Air quality and Climate Philadelphia, USA, July 22-27 2018. International Society for Indoor Air Quality and Climate (ISIAQ), 2018.

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title = "Airborne toxicity of a non-ionic alcohol ethoxylate surfactant and wetting agent used in cleaning chemicals",

abstract = "Information on the bioactivity of the surfactants present in cleaning chemicals and their effect on the indoor ecosystems of buildings are needed to provide safe cleaning practices and healthy indoor air. In this study, in vitro (murine neuroblastoma cells and porcine kidney epithelial cells) and ex vivo bioassays (boar sperm) were developed to measure the airborne toxicity of genapol X-080 (polyethylene glycol monoalkyl ethers), used as surfactant and wetting agent in indoor environments. The diffusion and toxicity of airborne genapol X-080 dilutions were demonstrated using two-compartment Petri dishes. Resazurin was also added, to test airborne diffusion of genapol X-080. This preliminary method proved that airborne diffusion of genapol X-080 was possible and toxic toward mammalian cells. Moreover, the ex vivo bioassays were ten times more sensitive. The resazurin + genapol X-080 test showed potential for developing a new and easy method to track the airborne diffusion of polyethylene glycol monoalkyl ethers used in buildings.",

keywords = "indoor air quality, non-ionic surfactant, genapol X-080, boar spermatozoa, somatic cell lines, Bioassays",

author = "Emmanuelle Castagnoli and M.A. Andersson and Raimo Mikkola and Jarek Kurnitski and Heidi Salonen",

year = "2018",

month = jul,

language = "English",

booktitle = "Proceedings Indoor Air 2018: The 15th international conference of Indoor Air quality and Climate Philadelphia, USA, July 22-27 2018",

publisher = "International Society for Indoor Air Quality and Climate (ISIAQ)",

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note = "Conference of the International Society of Indoor Air Quality and Climate , ISIAQ ; Conference date: 22-07-2018 Through 27-07-2018",

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Castagnoli, E , Andersson, MA , Mikkola, R , Kurnitski, J & Salonen, H 2018, Airborne toxicity of a non-ionic alcohol ethoxylate surfactant and wetting agent used in cleaning chemicals. in Proceedings Indoor Air 2018: The 15th international conference of Indoor Air quality and Climate Philadelphia, USA, July 22-27 2018., ID373, International Society for Indoor Air Quality and Climate (ISIAQ), Conference of the International Society of Indoor Air Quality and Climate , Philadelphia , Pennsylvania, United States, 22/07/2018.

Airborne toxicity of a non-ionic alcohol ethoxylate surfactant and wetting agent used in cleaning chemicals. / Castagnoli, Emmanuelle ; Andersson, M.A. ; Mikkola, Raimo et al.
Proceedings Indoor Air 2018: The 15th international conference of Indoor Air quality and Climate Philadelphia, USA, July 22-27 2018. International Society for Indoor Air Quality and Climate (ISIAQ), 2018. ID373.

Research output: Chapter in Book/Report/Conference proceeding › Conference article in proceedings › Professional

TY - GEN

T1 - Airborne toxicity of a non-ionic alcohol ethoxylate surfactant and wetting agent used in cleaning chemicals

AU - Castagnoli, Emmanuelle

AU - Andersson, M.A.

AU - Mikkola, Raimo

AU - Kurnitski, Jarek

AU - Salonen, Heidi

N1 - Conference code: 15

PY - 2018/7

Y1 - 2018/7

N2 - Information on the bioactivity of the surfactants present in cleaning chemicals and their effect on the indoor ecosystems of buildings are needed to provide safe cleaning practices and healthy indoor air. In this study, in vitro (murine neuroblastoma cells and porcine kidney epithelial cells) and ex vivo bioassays (boar sperm) were developed to measure the airborne toxicity of genapol X-080 (polyethylene glycol monoalkyl ethers), used as surfactant and wetting agent in indoor environments. The diffusion and toxicity of airborne genapol X-080 dilutions were demonstrated using two-compartment Petri dishes. Resazurin was also added, to test airborne diffusion of genapol X-080. This preliminary method proved that airborne diffusion of genapol X-080 was possible and toxic toward mammalian cells. Moreover, the ex vivo bioassays were ten times more sensitive. The resazurin + genapol X-080 test showed potential for developing a new and easy method to track the airborne diffusion of polyethylene glycol monoalkyl ethers used in buildings.

AB - Information on the bioactivity of the surfactants present in cleaning chemicals and their effect on the indoor ecosystems of buildings are needed to provide safe cleaning practices and healthy indoor air. In this study, in vitro (murine neuroblastoma cells and porcine kidney epithelial cells) and ex vivo bioassays (boar sperm) were developed to measure the airborne toxicity of genapol X-080 (polyethylene glycol monoalkyl ethers), used as surfactant and wetting agent in indoor environments. The diffusion and toxicity of airborne genapol X-080 dilutions were demonstrated using two-compartment Petri dishes. Resazurin was also added, to test airborne diffusion of genapol X-080. This preliminary method proved that airborne diffusion of genapol X-080 was possible and toxic toward mammalian cells. Moreover, the ex vivo bioassays were ten times more sensitive. The resazurin + genapol X-080 test showed potential for developing a new and easy method to track the airborne diffusion of polyethylene glycol monoalkyl ethers used in buildings.

KW - indoor air quality

KW - non-ionic surfactant

KW - genapol X-080

KW - boar spermatozoa

KW - somatic cell lines

KW - Bioassays

UR - https://www.isiaq.org/conference_proceedings.php

M3 - Conference article in proceedings

BT - Proceedings Indoor Air 2018: The 15th international conference of Indoor Air quality and Climate Philadelphia, USA, July 22-27 2018

PB - International Society for Indoor Air Quality and Climate (ISIAQ)

T2 - Conference of the International Society of Indoor Air Quality and Climate

Y2 - 22 July 2018 through 27 July 2018

ER -

Castagnoli E , Andersson MA , Mikkola R , Kurnitski J , Salonen H. Airborne toxicity of a non-ionic alcohol ethoxylate surfactant and wetting agent used in cleaning chemicals. In Proceedings Indoor Air 2018: The 15th international conference of Indoor Air quality and Climate Philadelphia, USA, July 22-27 2018. International Society for Indoor Air Quality and Climate (ISIAQ). 2018. ID373

Airborne toxicity of a non-ionic alcohol ethoxylate surfactant and wetting agent used in cleaning chemicals

Abstract

Conference

Keywords

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SIBI: Sisätiloissa käytettyjen siivouskemikaalien ja biosidien vaikutukset mitattuun ja koettuun sisäilman laatuun koulu- ja päiväkotirakennuksissa

Toxin transport mechanisms from moisture damaged structures to indoor air

Cite this

Airborne toxicity of a non-ionic alcohol ethoxylate surfactant and wetting agent used in cleaning chemicals

Abstract

Conference

Keywords

Other files and links

Fingerprint

Projects

SIBI: Sisätiloissa käytettyjen siivouskemikaalien ja biosidien vaikutukset mitattuun ja koettuun sisäilman laatuun koulu- ja päiväkotirakennuksissa

Toxin transport mechanisms from moisture damaged structures to indoor air

Cite this