A straightforward approach towards glycoamino acids and glycopeptidesviaPd-catalysed allylic alkylation

Research output: Contribution to journalArticle

Researchers

Research units

  • Saarland University

Abstract

Chelated enolates are versatile nucleophiles for palladium-catalysed allylic alkylations. Even with complex allylic substrates the reaction proceed without significant isomerisation. This allows the stereoselective introduction of polyhydroxylated allylic sidechains into amino acids and peptides with retention of the olefin geometry.

Details

Original languageEnglish
Pages (from-to)103-110
Number of pages8
JournalORGANIC AND BIOMOLECULAR CHEMISTRY
Volume7
Publication statusPublished - 24 Sep 2008
MoE publication typeA1 Journal article-refereed

ID: 11164085