Abstract
This paper describes the design of an integrated sensor interface for neurochemical signal acquisition. Neurochemicals undergo oxidation and reduction reactions in the presence of an action potential. Thus, knowledge of the oxidation and reduction potentials of neurochemicals is important in the neurostimulation treatment of neurological and neurodegenerative diseases. The sensor interface circuit utilizes a mixed-signal design to detect the induced current from the neurochemical, in response to an applied voltage. The circuit is fabricated in 65nm CMOS technology and supports a wide input current range of ±1.2μA with a current resolution of 85.4pA, enabling detection of neurochemicals within the supported current range. Measured results with dopamine concentration of 500nMol demonstrate the ability of the sensor interface circuit to detect oxidation and reduction current peaks, indicating the release times and the required oxidation and reduction potentials for neurostimulation of the neurochemical.
Original language | English |
---|---|
Title of host publication | 2019 IEEE 62nd International Midwest Symposium on Circuits and Systems, MWSCAS 2019 |
Publisher | IEEE |
Pages | 390-393 |
Number of pages | 4 |
ISBN (Electronic) | 9781728127880 |
DOIs | |
Publication status | Published - 1 Aug 2019 |
MoE publication type | A4 Conference publication |
Event | International Midwest Symposium on Circuits and Systems - Dallas, United States Duration: 4 Aug 2019 → 7 Aug 2019 Conference number: 62 |
Publication series
Name | Conference proceedings : Midwest Symposium on Circuits and Systems |
---|---|
ISSN (Print) | 1548-3746 |
ISSN (Electronic) | 1558-3899 |
Conference
Conference | International Midwest Symposium on Circuits and Systems |
---|---|
Abbreviated title | MWSCAS |
Country/Territory | United States |
City | Dallas |
Period | 04/08/2019 → 07/08/2019 |
Fingerprint
Dive into the research topics of 'A Sensor Interface for Neurochemical Signal Acquisition'. Together they form a unique fingerprint.Equipment
-
Aalto Electronics-ICT
Ryynänen, J. (Manager)
Department of Electronics and NanoengineeringFacility/equipment: Facility
-
Prizes
-
A Sensor Interface for Neurochemical Signal Acquisition
Olabode, O. (Recipient), 6 Aug 2019
Prize: Award or honor granted for a specific work