A current controlled oscillator based readout front-end for neurochemical sensing in 65nm CMOS technology

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    Abstract

    This paper presents the design of an integrated current-controlled oscillator (CCO) based readout front-end for neurochemical sensing applications. The readout front-end chip is implemented in 65 nm CMOS technology and occupies an area of 0.059 mm2. The proposed design supports an input current range of 1.2 μA (±600 nA) and can also be configured to support wider current range. The CCO-based structure utilized in this design results in noise averaging of the detected neurochemical input signal due to its inherent ΔΣfirst-order noise shaping and anti-alias filtering characteristics. Thus, the prototype chip achieves a current resolution of 100 pA and can detect dopamine concentrations as small as 10 μMol based on measured data from novel diamond-like carbon electrodes. In addition, the digital codes obtained from the readout front-end attain a signal-to-noise (SNR) of 82 dB and linearity limited effective-number-of-bits (ENOB) of 8 at full current range input, without employing any calibration or linearization techniques. The proposed read-out front-end consumes 33.7 μW of power in continuous operation.

    Original languageEnglish
    Title of host publicationISCAS 2016 - IEEE International Symposium on Circuits and Systems
    PublisherIEEE
    Pages514-517
    Number of pages4
    ISBN (Electronic)9781479953400, 978-1-4799-5341-7
    ISBN (Print)978-1-4799-5342-4
    DOIs
    Publication statusPublished - 11 Aug 2016
    MoE publication typeA4 Article in a conference publication
    EventIEEE International Symposium on Circuits and Systems - Montreal, Canada
    Duration: 22 May 201625 May 2016
    http://iscas2016.org/

    Publication series

    NameIEEE International Symposium on Circuits and Systems
    PublisherIEEE
    ISSN (Print)0271-4302
    ISSN (Electronic)2158-1525

    Conference

    ConferenceIEEE International Symposium on Circuits and Systems
    Abbreviated titleISCAS
    CountryCanada
    CityMontreal
    Period22/05/201625/05/2016
    Internet address

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