A current controlled oscillator based readout front-end for neurochemical sensing in 65nm CMOS technology

Olaitan Olabode; Marko Kosunen; Kari Halonen

doi:10.1109/ISCAS.2016.7527290

A current controlled oscillator based readout front-end for neurochemical sensing in 65nm CMOS technology

Olaitan Olabode, Marko Kosunen, Kari Halonen

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Scientific › peer-review

4 Citations (Scopus)

183 Downloads (Pure)

Abstract

This paper presents the design of an integrated current-controlled oscillator (CCO) based readout front-end for neurochemical sensing applications. The readout front-end chip is implemented in 65 nm CMOS technology and occupies an area of 0.059 mm2. The proposed design supports an input current range of 1.2 μA (±600 nA) and can also be configured to support wider current range. The CCO-based structure utilized in this design results in noise averaging of the detected neurochemical input signal due to its inherent ΔΣfirst-order noise shaping and anti-alias filtering characteristics. Thus, the prototype chip achieves a current resolution of 100 pA and can detect dopamine concentrations as small as 10 μMol based on measured data from novel diamond-like carbon electrodes. In addition, the digital codes obtained from the readout front-end attain a signal-to-noise (SNR) of 82 dB and linearity limited effective-number-of-bits (ENOB) of 8 at full current range input, without employing any calibration or linearization techniques. The proposed read-out front-end consumes 33.7 μW of power in continuous operation.

Original language	English
Title of host publication	ISCAS 2016 - IEEE International Symposium on Circuits and Systems
Publisher	IEEE
Pages	514-517
Number of pages	4
ISBN (Electronic)	9781479953400, 978-1-4799-5341-7
ISBN (Print)	978-1-4799-5342-4
DOIs	https://doi.org/10.1109/ISCAS.2016.7527290
Publication status	Published - 11 Aug 2016
MoE publication type	A4 Article in a conference publication
Event	IEEE International Symposium on Circuits and Systems - Montreal, Canada Duration: 22 May 2016 → 25 May 2016 http://iscas2016.org/

Publication series

Name	IEEE International Symposium on Circuits and Systems
Publisher	IEEE
ISSN (Print)	0271-4302
ISSN (Electronic)	2158-1525

Conference

Conference	IEEE International Symposium on Circuits and Systems
Abbreviated title	ISCAS
Country	Canada
City	Montreal
Period	22/05/2016 → 25/05/2016
Internet address	http://iscas2016.org/

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title = "A current controlled oscillator based readout front-end for neurochemical sensing in 65nm CMOS technology",

abstract = "This paper presents the design of an integrated current-controlled oscillator (CCO) based readout front-end for neurochemical sensing applications. The readout front-end chip is implemented in 65 nm CMOS technology and occupies an area of 0.059 mm2. The proposed design supports an input current range of 1.2 μA (±600 nA) and can also be configured to support wider current range. The CCO-based structure utilized in this design results in noise averaging of the detected neurochemical input signal due to its inherent ΔΣfirst-order noise shaping and anti-alias filtering characteristics. Thus, the prototype chip achieves a current resolution of 100 pA and can detect dopamine concentrations as small as 10 μMol based on measured data from novel diamond-like carbon electrodes. In addition, the digital codes obtained from the readout front-end attain a signal-to-noise (SNR) of 82 dB and linearity limited effective-number-of-bits (ENOB) of 8 at full current range input, without employing any calibration or linearization techniques. The proposed read-out front-end consumes 33.7 μW of power in continuous operation.",

author = "Olaitan Olabode and Marko Kosunen and Kari Halonen",

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Olabode, O , Kosunen, M & Halonen, K 2016, A current controlled oscillator based readout front-end for neurochemical sensing in 65nm CMOS technology. in ISCAS 2016 - IEEE International Symposium on Circuits and Systems., 7527290, IEEE International Symposium on Circuits and Systems, IEEE, pp. 514-517, IEEE International Symposium on Circuits and Systems, Montreal, Canada, 22/05/2016. https://doi.org/10.1109/ISCAS.2016.7527290

A current controlled oscillator based readout front-end for neurochemical sensing in 65nm CMOS technology. / Olabode, Olaitan ; Kosunen, Marko ; Halonen, Kari.

ISCAS 2016 - IEEE International Symposium on Circuits and Systems. IEEE, 2016. p. 514-517 7527290 (IEEE International Symposium on Circuits and Systems).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Scientific › peer-review

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N2 - This paper presents the design of an integrated current-controlled oscillator (CCO) based readout front-end for neurochemical sensing applications. The readout front-end chip is implemented in 65 nm CMOS technology and occupies an area of 0.059 mm2. The proposed design supports an input current range of 1.2 μA (±600 nA) and can also be configured to support wider current range. The CCO-based structure utilized in this design results in noise averaging of the detected neurochemical input signal due to its inherent ΔΣfirst-order noise shaping and anti-alias filtering characteristics. Thus, the prototype chip achieves a current resolution of 100 pA and can detect dopamine concentrations as small as 10 μMol based on measured data from novel diamond-like carbon electrodes. In addition, the digital codes obtained from the readout front-end attain a signal-to-noise (SNR) of 82 dB and linearity limited effective-number-of-bits (ENOB) of 8 at full current range input, without employing any calibration or linearization techniques. The proposed read-out front-end consumes 33.7 μW of power in continuous operation.

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A current controlled oscillator based readout front-end for neurochemical sensing in 65nm CMOS technology

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