4-D PET-MR with volumetric navigators and compressed sensing

Stefano Pedemonte*, Ciprian Catana, Koen Van Leemput

*Corresponding author for this work

Research output: Contribution to journalArticleScientificpeer-review

1 Citation (Scopus)

Abstract

Hybrid PET-MR scanners acquire multi-modal signals simultaneously, eliminating the requirement of software alignment between the MR and PET imaging data. However, the acquisition of high-resolution MR and PET images requires long scanning times, thereforemovement of the subject during the acquisition deteriorates both the PET and theMR images. In this work we have developed an approach for tightly integrated PET-MR imaging, making use of volumetric MR navigators to inform, in real-time, both the MR acquisition and the PET reconstruction. The integrated imaging procedure that we describe exploits the simultaneity of MR and PET in hybrid PET-MR systems, producing inherently-aligned motion-free MR and PET images. We describe the system setup, the algorithm for motion-corrected reconstruction, an adaptive sinogram binning algorithm and software design decisions aimed at integrating tightly the MR and PET subsystems. Application of the integrated motion-corrected acquisition procedure to a phantom study and to a volunteer subject demonstrates the validity of the approach for a variety of motion patterns.

Original languageEnglish
Pages (from-to)93-101
Number of pages9
JournalLecture Notes in Computational Vision and Biomechanics
Volume22
DOIs
Publication statusPublished - 2015
MoE publication typeA1 Journal article-refereed

Keywords

  • 4-D Tomographic reconstruction
  • Motion aware imaging
  • Unified PET-MR

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